Ácido úrico: una molécula con acciones paradójicas en la insuficiencia cardiaca

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Published inRevista medíca de Chile Vol. 139; no. 4; pp. 505 - 515
Main Authors Alcaíno, Hernán, Greig, Douglas, Castro, Pablo, Verdejo, Hugo, Mellado, Rosemarie, García, Lorena, Díaz-Araya, Guillermo, Quiroga, Clara, Chiong, Mario, Lavandero, Sergio
Format Journal Article
LanguageEnglish
Portuguese
Published Sociedad Médica de Santiago 01.04.2011
Subjects
MEDICINE, GENERAL & INTERNAL
Heart failure
Oxidative stress
Uric acid
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Author Lavandero, Sergio
García, Lorena
Greig, Douglas
Quiroga, Clara
Chiong, Mario
Alcaíno, Hernán
Verdejo, Hugo
Mellado, Rosemarie
Díaz-Araya, Guillermo
Castro, Pablo
AuthorAffiliation Pontificia Universidad Católica de Chile
Universidad de Valparaíso
Universidad de Chile
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CitedBy_id crossref_primary_10_1016_j_jacc_2012_01_077
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crossref_primary_10_1016_j_arteri_2018_09_001
ContentType Journal Article
Copyright This work is licensed under a Creative Commons Attribution 4.0 International License.
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DocumentTitleAlternate The role of uric acid in heart failure
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Issue 4
Keywords Heart failure
Oxidative stress
Uric acid
Language English
Portuguese
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References Castro, G P; Verdejo, PH; Vukasovic, JL; Garcés, E; González, I 2006; 134
Waud, WR; Rajagopalan, KV 1976; 172
Farquharson, CA; Butler, R; Hill, A; Belch, JJ; Struthers, AD 2002; 106
Suzuki, I; Yamauchi, T; Onuma, M; Nozaki, S 2009; 45
Doehner, W; Springer, J; Landmesser, U; Struthers, AD; Anker, SD 2008; 10
Cengel, A; Turkoglu, S; Turfan, M; Boyaci, B 2005; 60
Verdejo, H; Alcaíno, H; Greig, D; García, L; Pizarro, M; Chiong, M 2008; 10
Patterson, RA; Horsley, ET; Leake, DS 2003; 44
Nakagawa, T; Cirillo, P; Sato, W; Gersch, M; Sautin, Y; Roncal, C 2008; 3
De, AC; Turner, ST; Kullo, IJ 2007; 21
Becker, BF; Reinholz, N; Ozcelik, T; Leipert, B; Gerlach, E 1989; 415
Brodov, Y; Chouraqui, P; Goldenberg, I; Boyko, V; Mandelzweig, L; Behar, S 2009; 114
Schlotte, V; Sevanian, A; Hochstein, P; Weithmann, KU 1998; 25
Murray, AJ; Edwards, LM; Clarke, K 2007; 10
Kang, DH; Han, L; Ouyang, X; Kahn, AM; Kanellis, J; Li, P 2005; 25
Johnson, RJ; Rivard, C; Nakagawa, T; Sautin, YY; Sánchez-Lozada, LG 2009; 22
Nakanishi, N; Suzuki, K; Kawashimo, H; Nakamura, K; Tatara, K 1999; 9
Sarnesto, A; Linder, N; Raivio, KO 1996; 74
Alcaíno, H; Greig, D; Chiong, M; Verdejo, H; Miranda, R; Concepción, R 2008; 10
Hare, JM; Mangal, B; Brown, J; Fisher, CJr; Freudenberger, R; Colucci, WS 2008; 51
Gavin, AD; Struthers, AD 2005; 91
Nieto, FJ; Iribarren, C; Gross, MD; Comstock, GW; Cutler, RG 2000; 148
Landmesser, U; Spiekermann, S; Dikalov, S; Tatge, H; Wilke, R; Kohler, C 2002; 106
Langlois, M; De-Bacquer, D; Duprez, D; De Buyzere, M; Delanghe, J; Blaton, V 2003; 168
Miranda, HR; Castro, GP; Verdejo, PH; Chiong, M; Díaz-Araya, G; Mellado, R 2007; 135
Nishino, T 1994; 116
Linder, N; Rapola, J; Raivio, KO 1999; 79
Pascual-Figal, DA; Hurtado-Martínez, JA; Redondo, B; Antolinos, MJ; Ruiperez, JA; Valdés, M 2007; 9
García, PJ; Mateos, FA 1994; 16
Sautin, YY; Johnson, RJ 2008; 27
George, J; Carr, E; Davies, J; Belch, JJ; Struthers, A 2006; 114
Sakai, H; Tsutamoto, T; Tsutsui, T; Tanaka, T; Ishikawa, C; Horie, M 2006; 70
Johnson, RJ; Titte, S; Cade, JR; Rideout, BA; Oliver, WJ 2005; 25
Kanellis, J; Watanabe, S; Li, JH; Kang, DH; Li, P; Nakagawa, T 2003; 41
Nystrom, T 2008; 40
Cnossen, JS; Ruyter-Hanhijarvi, H; Van-der-Post, JA; Mol, BW; Khan, KS; Ter Riet, G 2006; 85
Greig, D; Castro, P; Gabrielli, L; Miranda, R; Verdejo, H; Alcaino, H 2008; 136
Vukasovic, JL; Castro, G P; Sepúlveda, ML; Nazzal, NC; Garcés, FE; Concepción, CR 2006; 134
Shehab, AM; Butler, R; Macfadyen, RJ; Struthers, AD 2001; 51
Ekundayo, OJ; Dell'italia, LJ; Sanders, PW; Arnett, D; Aban, I; Love, TE 2009
Waring, WS; Convery, A; Mishra, V; Shenkin, A; Webb, DJ; Maxwell, SR 2003; 105
Lin, WT; Yang, SC; Tsai, SC; Huang, CC; Lee, NY 2006; 95
Gavella, M; Lipovac, V; Vucic, M; Rocic, B 1997; 29
Kang, DH; Park, SK; Lee, IK; Johnson, RJ 2005; 16
Cappola, TP; Kass, DA; Nelson, GS; Berger, RD; Rosas, GO; Kobeissi, ZA 2001; 104
Meadows, J; Smith, RC 1987; 43
Martínez, A; González, A; Cerda, C; Pérez, P; Castro, P; Pérez, O 2004; 132
Muraoka, S; Miura, T 2003; 93
Kim, KM; Henderson, GN; Ouyang, X; Frye, RF; Sautin, YY; Feig, DI 2009; 877
De-Jong, JW; Van-der, MP; Nieukoop, AS; Huizer, T; Stroeve, RJ; Bos, E 1990; 67
Tousoulis, D; Charakida, M; Stefanadis, C 2005; 100
Lainscak, M; Von-Haehling, S; Springer, J; Anker, SD 2007; 5
Niizeki, T; Takeishi, Y; Arimoto, T; Okuyama, H; Nozaki, N; Hirono, O 2006; 47
Della, CE; Gozzetti, G; Novello, F; Stirpe, F 1969; 191
Felici, C; Ciari, I; Terzuoli, L; Porcelli, B; Setacci, C; Giubbolini, M 2006; 25
Doehner, W; Schoene, N; Rauchhaus, M; Leyva-León, F; Pavitt, DV; Reaveley, DA 2002; 105
Johnson, RJ; Gaucher, EA; Sautin, YY; Henderson, GN; Angerhofer, AJ; Benner, SA 2008; 71
Brand, FN; Mc-Gee, DL; Kannel, WB; Stokes, J III; Castelli, WP 1985; 121
Riches, PL; Wright, AF; Ralston, SH 2009; 18
Anker, SD; Doehner, W; Rauchhaus, M; Sharma, R; francis, D; Knosalla, C 2003; 107
Jaramillo, M; Godbout, M; Naccache, PH; Olivier, M 2004; 279
Jankowska, EA; Ponikowska, B; Majda, J; Zymlinski, R; Trzaska, M; Reczuch, K 2007; 115
Castro, P; Vukasovic, JL; Garcés, E; Sepúlveda, L; Ferrada, M; Alvarado, S 2004; 132
Spitsin, SV; Scott, GS; Mikheeva, T; Zborek, A; Kean, RB; Brimer, CM 2002; 33
Tan, S; Radi, R; Gaudier, F; Evans, RA; Rivera, A; Kirk, KA 1993; 34
Alwan, WH; Dieppe, PA; Elson, CJ; Bradfeld, JW 1989; 48
Seddon, M; Looi, YH; Shah, AM 2007; 93
Rosca, MG; Hoppel, CL 2009; 41
Feig, DI 2009; 18
Lippi, G; Montagnana, M; Franchini, M; Favaloro, EJ; Targher, G 2008; 392
Mandell, BF 2002; 69
Reyes, AJ; Leary, WP 2003; 21
Hille, R; Massey, V 1981; 256
Reyes, AJ; Leary, WP 2002; 16
Mazzali, M; Hughes, J; Kim, YG; Jefferson, JA; Kang, DH; Gordon, KL 2001; 38
Sevanian, A; Davies, KJ; Hochstein, P 1991; 54
Souza, AV; Petretski, JH; Demasi, M; Bechara, EJ; Oliveira, PL 1997; 22
Brodov, Y; Behar, S; Goldenberg, I; Boyko, V; Chouraqui, P 2009; 104
Cingolani, HE; Plastino, JA; Escudero, EM; Mangal, B; Brown, J; Pérez, NG 2006; 12
Berry, CE; Hare, JM 2004; 555
Lainscak, M; Anker, SD 2009; 34
Hink, HU; Santanam, N; Dikalov, S; Mccann, L; Nguyen, AD; Parthasarathy, S 2002; 22
Reyes, AJ 2005; 7
Hsu, CC; Yin, MC; Tian, R 2005; 19
Hare, JM; Johnson, RJ 2003; 107
Khosla, UM; Zharikov, S; Finch, JL; Nakagawa, T; Roncal, C; Mu, W 2005; 67
Chamorro, A; Planas, AM; Muner, DS; Deulofeu, R 2004; 62
Shi, Y; Evans, JE; Rock, KL 2003; 425
References_xml – volume: 555
  start-page: 589
  year: 2004
  end-page: 606
  article-title: Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and patho physiological implications
  publication-title: J Physiol
  contributor:
    fullname: Berry, CE; Hare, JM
– year: 2009
  article-title: Association between hyperuricemia and incident heart failure among older adults: a propensity matched study
  publication-title: Int J Cardiol
  contributor:
    fullname: Ekundayo, OJ; Dell'italia, LJ; Sanders, PW; Arnett, D; Aban, I; Love, TE
– volume: 62
  start-page: 173
  year: 2004
  end-page: 6
  article-title: Uric acid administration for neuroprotection in patients with acute brain ischemia
  publication-title: Med Hypotheses
  contributor:
    fullname: Chamorro, A; Planas, AM; Muner, DS; Deulofeu, R
– volume: 114
  start-page: 300
  year: 2009
  end-page: 5
  article-title: Serum uric acid for risk stratifcation of patients with coronary artery disease
  publication-title: Cardiology
  contributor:
    fullname: Brodov, Y; Chouraqui, P; Goldenberg, I; Boyko, V; Mandelzweig, L; Behar, S
– volume: 100
  start-page: 347
  year: 2005
  end-page: 53
  article-title: Infammation and endothelial dysfunction as therapeutic targets in patients with heart failure
  publication-title: Int J Cardiol
  contributor:
    fullname: Tousoulis, D; Charakida, M; Stefanadis, C
– volume: 18
  start-page: R177
  year: 2009
  end-page: 84
  article-title: Recent insights into the pathogenesis of hyperuricaemia and gout
  publication-title: Hum Mol Genet
  contributor:
    fullname: Riches, PL; Wright, AF; Ralston, SH
– volume: 22
  start-page: 952
  year: 2009
  end-page: 3
  article-title: Uric acid: more to learn, more experiments to do
  publication-title: Am J Hypertens
  contributor:
    fullname: Johnson, RJ; Rivard, C; Nakagawa, T; Sautin, YY; Sánchez-Lozada, LG
– volume: 67
  start-page: 770
  year: 1990
  end-page: 3
  article-title: Xanthine oxidoreductase activity in perfused hearts of various species including humans
  publication-title: Circ Res
  contributor:
    fullname: De-Jong, JW; Van-der, MP; Nieukoop, AS; Huizer, T; Stroeve, RJ; Bos, E
– volume: 9
  start-page: 99
  year: 1999
  end-page: 106
  article-title: Serum uric acid: correlation with biological clinical and behavioral factors in Japanese men
  publication-title: J Epidemiol
  contributor:
    fullname: Nakanishi, N; Suzuki, K; Kawashimo, H; Nakamura, K; Tatara, K
– volume: 16
  start-page: 40
  year: 1994
  end-page: 54
  article-title: Clinical and biochemical aspects of uric acid overproduction
  publication-title: Pharm World Sci
  contributor:
    fullname: García, PJ; Mateos, FA
– volume: 132
  start-page: 655
  year: 2004
  end-page: 62
  article-title: Cardiac failure in Chilean hospitals: results of the National Registry of Heart Failure ICARO
  publication-title: Rev Med Chile
  contributor:
    fullname: Castro, P; Vukasovic, JL; Garcés, E; Sepúlveda, L; Ferrada, M; Alvarado, S
– volume: 40
  start-page: 593
  year: 2008
  end-page: 606
  article-title: The potential beneficial role of glucagon like peptide 1 in endothelial dysfunction and heart failure associated with insulin resistance
  publication-title: Horm Metab Res
  contributor:
    fullname: Nystrom, T
– volume: 67
  start-page: 1739
  year: 2005
  end-page: 42
  article-title: Hyperuricemia induces endothelial dysfunction
  publication-title: Kidney Int
  contributor:
    fullname: Khosla, UM; Zharikov, S; Finch, JL; Nakagawa, T; Roncal, C; Mu, W
– volume: 115
  start-page: 151
  year: 2007
  end-page: 5
  article-title: Hyperuricaemia predicts poor outcome in patients with mild to moderate chronic heart failure
  publication-title: Int J Cardiol
  contributor:
    fullname: Jankowska, EA; Ponikowska, B; Majda, J; Zymlinski, R; Trzaska, M; Reczuch, K
– volume: 27
  start-page: 608
  year: 2008
  end-page: 19
  article-title: Uric acid: the oxidant antioxidant paradox
  publication-title: Nucleosides Nucleotides Nucleic acids
  contributor:
    fullname: Sautin, YY; Johnson, RJ
– volume: 104
  start-page: 194
  year: 2009
  end-page: 8
  article-title: Usefulness of combining serum uric acid and c-reactive protein for risk stratifcation of patients with coronary artery disease (bezafibrate Infarction Prevention [bIP] study)
  publication-title: Am J Cardiol
  contributor:
    fullname: Brodov, Y; Behar, S; Goldenberg, I; Boyko, V; Chouraqui, P
– volume: 91
  start-page: 749
  year: 2005
  end-page: 53
  article-title: Allopurinol reduces b-type natriuretic peptide concentrations and haemoglobin but does not alter exercise capacity in chronic heart failure
  publication-title: Heart
  contributor:
    fullname: Gavin, AD; Struthers, AD
– volume: 48
  start-page: 476
  year: 1989
  end-page: 82
  article-title: Hydroxyapatite and urate crystal induced cytokine release by macrophages
  publication-title: Ann Rheum Dis
  contributor:
    fullname: Alwan, WH; Dieppe, PA; Elson, CJ; Bradfeld, JW
– volume: 16
  start-page: 3553
  year: 2005
  end-page: 62
  article-title: Uric acid induced c-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells
  publication-title: J Am Soc Nephrol
  contributor:
    fullname: Kang, DH; Park, SK; Lee, IK; Johnson, RJ
– volume: 121
  start-page: 11
  year: 1985
  end-page: 8
  article-title: Hyperuricemia as a risk factor of coronary heart disease: The framingham Study
  publication-title: Am J Epidemiol
  contributor:
    fullname: Brand, FN; Mc-Gee, DL; Kannel, WB; Stokes, J III; Castelli, WP
– volume: 10
  start-page: 704
  year: 2007
  end-page: 11
  article-title: Mitochondria and heart failure
  publication-title: Curr Opin Clin Nutr Metab Care
  contributor:
    fullname: Murray, AJ; Edwards, LM; Clarke, K
– volume: 60
  start-page: 489
  year: 2005
  end-page: 92
  article-title: Serum uric acid levels as a predictor of in hospital death in patients hospitalized for decompensated heart failure
  publication-title: Acta Cardiol
  contributor:
    fullname: Cengel, A; Turkoglu, S; Turfan, M; Boyaci, B
– volume: 18
  start-page: 526
  year: 2009
  end-page: 30
  article-title: Uric acid: a novel mediator and marker of risk in chronic kidney disease?
  publication-title: Curr Opin Nephrol Hypertens
  contributor:
    fullname: Feig, DI
– volume: 134
  start-page: 1083
  year: 2006
  end-page: 91
  article-title: Predictors of hospital death and prolonged hospitalization in patients with cardiac failure in Chilean hospitals
  publication-title: Rev Med Chile
  contributor:
    fullname: Castro, G P; Verdejo, PH; Vukasovic, JL; Garcés, E; González, I
– volume: 43
  start-page: 410
  year: 1987
  end-page: 6
  article-title: Uric acid protects erythrocytes from ozone-induced changes
  publication-title: Environ Res
  contributor:
    fullname: Meadows, J; Smith, RC
– volume: 191
  start-page: 164
  year: 1969
  end-page: 6
  article-title: Properties of the xanthine oxidase from human liver
  publication-title: Biochim Biophys Acta
  contributor:
    fullname: Della, CE; Gozzetti, G; Novello, F; Stirpe, F
– volume: 10
  start-page: 1271
  year: 2008
  end-page: 2
  article-title: Uric acid, xanthine oxidase and heart failure: unresolved issues
  publication-title: Eur J Heart Fail
  contributor:
    fullname: Verdejo, H; Alcaíno, H; Greig, D; García, L; Pizarro, M; Chiong, M
– volume: 136
  start-page: 687
  year: 2008
  end-page: 93
  article-title: Infammation and endothelial dysfunction in patients with chronic heart failure
  publication-title: Rev Med Chile
  contributor:
    fullname: Greig, D; Castro, P; Gabrielli, L; Miranda, R; Verdejo, H; Alcaino, H
– volume: 107
  start-page: 1951
  year: 2003
  end-page: 3
  article-title: Uric acid predicts clinical outcomes in heart failure: insights regarding the role of xan thine oxidase and uric acid in disease pathophysiology
  publication-title: Circulation
  contributor:
    fullname: Hare, JM; Johnson, RJ
– volume: 71
  start-page: 22
  year: 2008
  end-page: 31
  article-title: The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease
  publication-title: Med Hypotheses
  contributor:
    fullname: Johnson, RJ; Gaucher, EA; Sautin, YY; Henderson, GN; Angerhofer, AJ; Benner, SA
– volume: 34
  start-page: 303
  year: 1993
  end-page: 7
  article-title: Physiologic levels of uric acid inhibit xanthine oxidase in human plasma
  publication-title: Pediatr Res
  contributor:
    fullname: Tan, S; Radi, R; Gaudier, F; Evans, RA; Rivera, A; Kirk, KA
– volume: 12
  start-page: 491
  year: 2006
  end-page: 8
  article-title: The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study
  publication-title: J Card Fail
  contributor:
    fullname: Cingolani, HE; Plastino, JA; Escudero, EM; Mangal, B; Brown, J; Pérez, NG
– volume: 47
  start-page: 219
  year: 2006
  end-page: 28
  article-title: Hyperuricemia associated with high cardiac event rates in the elderly with chronic heart failure
  publication-title: J Cardiol
  contributor:
    fullname: Niizeki, T; Takeishi, Y; Arimoto, T; Okuyama, H; Nozaki, N; Hirono, O
– volume: 25
  start-page: 839
  year: 1998
  end-page: 47
  article-title: Effect of uric acid and chemical analogues on oxidation of human low density lipoprotein in vitro
  publication-title: Free Radic Biol Med
  contributor:
    fullname: Schlotte, V; Sevanian, A; Hochstein, P; Weithmann, KU
– volume: 41
  start-page: 107
  year: 2009
  end-page: 12
  article-title: New aspects of impaired mitochondrial function in heart failure
  publication-title: J Bioenerg Biomembr
  contributor:
    fullname: Rosca, MG; Hoppel, CL
– volume: 25
  start-page: 425
  year: 2005
  end-page: 33
  article-title: Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter
  publication-title: Am J Nephrol
  contributor:
    fullname: Kang, DH; Han, L; Ouyang, X; Kahn, AM; Kanellis, J; Li, P
– volume: 135
  start-page: 1056
  year: 2007
  end-page: 63
  article-title: Oxidative stress andinflammation in heart failure: mechanisms of damage and therapeutic alternatives
  publication-title: Rev Med Chile
  contributor:
    fullname: Miranda, HR; Castro, GP; Verdejo, PH; Chiong, M; Díaz-Araya, G; Mellado, R
– volume: 51
  start-page: 2301
  year: 2008
  end-page: 9
  article-title: Impact of oxypurinol in patients with symptomatic heart failure: Results of the OPT-CHF study
  publication-title: J Am Coll Cardiol
  contributor:
    fullname: Hare, JM; Mangal, B; Brown, J; Fisher, CJr; Freudenberger, R; Colucci, WS
– volume: 70
  start-page: 1006
  year: 2006
  end-page: 11
  article-title: Serum level of uric acid partly secreted from the failing heart is a prognostic marker in patients with congestive heart failure
  publication-title: Circ J
  contributor:
    fullname: Sakai, H; Tsutamoto, T; Tsutsui, T; Tanaka, T; Ishikawa, C; Horie, M
– volume: 22
  start-page: 1402
  year: 2002
  end-page: 8
  article-title: Peroxidase properties of extracellular superoxide dismutase: role of uric acid in modulating in vivo activity
  publication-title: Arterioscler Thromb Vasc biol
  contributor:
    fullname: Hink, HU; Santanam, N; Dikalov, S; Mccann, L; Nguyen, AD; Parthasarathy, S
– volume: 172
  start-page: 354
  year: 1976
  end-page: 64
  article-title: Purifcation and properties of the NaD+dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase
  publication-title: Arch Biochem Biophys
  contributor:
    fullname: Waud, WR; Rajagopalan, KV
– volume: 34
  start-page: 141
  year: 2009
  end-page: 7
  article-title: Prognostic factors in chronic heart failure
  publication-title: a review of serum biomarkers metabolic changes symptoms, and scoring systems. Herz
  contributor:
    fullname: Lainscak, M; Anker, SD
– volume: 132
  start-page: 1031
  year: 2004
  end-page: 36
  article-title: Prognostic value of hyperuricemia in chronic heart failure
  publication-title: Rev Med Chile
  contributor:
    fullname: Martínez, A; González, A; Cerda, C; Pérez, P; Castro, P; Pérez, O
– volume: 74
  start-page: 48
  year: 1996
  end-page: 56
  article-title: Organ distribution and molecular forms of human xanthine dehydrogenase/xanthine oxidase protein
  publication-title: Lab Invest
  contributor:
    fullname: Sarnesto, A; Linder, N; Raivio, KO
– volume: 85
  start-page: 519
  year: 2006
  end-page: 25
  article-title: Accuracy of serum uric acid determination in predicting pre-eclampsia: a systematic review
  publication-title: Acta Obstet Gynecol Scand
  contributor:
    fullname: Cnossen, JS; Ruyter-Hanhijarvi, H; Van-der-Post, JA; Mol, BW; Khan, KS; Ter Riet, G
– volume: 168
  start-page: 163
  year: 2003
  end-page: 8
  article-title: Serum uric acid in hypertensive patients with and without peripheral arterial disease
  publication-title: Atherosclerosis
  contributor:
    fullname: Langlois, M; De-Bacquer, D; Duprez, D; De Buyzere, M; Delanghe, J; Blaton, V
– volume: 5
  start-page: 77
  year: 2007
  end-page: 82
  article-title: Biomarkers for chronic heart failure
  publication-title: Heart Fail Monit
  contributor:
    fullname: Lainscak, M; Von-Haehling, S; Springer, J; Anker, SD
– volume: 51
  start-page: 329
  year: 2001
  end-page: 34
  article-title: A placebo controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure
  publication-title: Br J Clin Pharmacol
  contributor:
    fullname: Shehab, AM; Butler, R; Macfadyen, RJ; Struthers, AD
– volume: 44
  start-page: 512
  year: 2003
  end-page: 21
  article-title: Prooxidant and antioxidant properties of human serum ultrafltrates toward LDL: important role of uric acid
  publication-title: J Lipid Res
  contributor:
    fullname: Patterson, RA; Horsley, ET; Leake, DS
– volume: 114
  start-page: 2508
  year: 2006
  end-page: 16
  article-title: Highdose allopurinol improves endothelial function by profoundly reducing vascular oxidative stress and not by lowering uric acid
  publication-title: Circulation
  contributor:
    fullname: George, J; Carr, E; Davies, J; Belch, JJ; Struthers, A
– volume: 29
  start-page: 29
  year: 1997
  end-page: 35
  article-title: Evaluation of ascorbate and urate antioxidant capacity in human semen
  publication-title: Andrologia
  contributor:
    fullname: Gavella, M; Lipovac, V; Vucic, M; Rocic, B
– volume: 54
  start-page: 1129S
  year: 1991
  end-page: 34S
  article-title: Serum urate as an antioxidant for ascorbic acid
  publication-title: Am J Clin Nutr
  contributor:
    fullname: Sevanian, A; Davies, KJ; Hochstein, P
– volume: 105
  start-page: 425
  year: 2003
  end-page: 30
  article-title: Uric acid reduces exercise-induced oxidative stress in healthy adults
  publication-title: Clin Sci Lond
  contributor:
    fullname: Waring, WS; Convery, A; Mishra, V; Shenkin, A; Webb, DJ; Maxwell, SR
– volume: 3
  start-page: 313
  year: 2008
  end-page: 8
  article-title: The conundrum of hyperuricemia metabolic syndrome and renal disease
  publication-title: Intern Emerg Med
  contributor:
    fullname: Nakagawa, T; Cirillo, P; Sato, W; Gersch, M; Sautin, Y; Roncal, C
– volume: 134
  start-page: 539
  year: 2006
  end-page: 48
  article-title: Characteristics of heart failure with preserved ejection fraction: results of the Chilean national registry of heart failure ICARO
  publication-title: Rev Med Chile
  contributor:
    fullname: Vukasovic, JL; Castro, G P; Sepúlveda, ML; Nazzal, NC; Garcés, FE; Concepción, CR
– volume: 107
  start-page: 1991
  year: 2003
  end-page: 7
  article-title: Uric acid and survival in chronic heart failure: validation and application in metabolic functional and hemodynamic staging
  publication-title: Circulation
  contributor:
    fullname: Anker, SD; Doehner, W; Rauchhaus, M; Sharma, R; francis, D; Knosalla, C
– volume: 21
  start-page: 1775
  year: 2003
  end-page: 77
  article-title: The increase in serum uric acid induced by diuretics could be beneficial to cardiovascular prognosis in hypertension: a hypothesis
  publication-title: J Hypertens
  contributor:
    fullname: Reyes, AJ; Leary, WP
– volume: 425
  start-page: 516
  year: 2003
  end-page: 21
  article-title: Molecular identification of a danger signal that alerts the immune system to dying cells
  publication-title: Nature
  contributor:
    fullname: Shi, Y; Evans, JE; Rock, KL
– volume: 9
  start-page: 518
  year: 2007
  end-page: 24
  article-title: Hyperuricaemia and longterm outcome after hospital discharge in acute heart failure patients
  publication-title: Eur J Heart fail
  contributor:
    fullname: Pascual-Figal, DA; Hurtado-Martínez, JA; Redondo, B; Antolinos, MJ; Ruiperez, JA; Valdés, M
– volume: 93
  start-page: 284
  year: 2003
  end-page: 9
  article-title: Inhibition by uric acid of free radicals that damage biological molecules
  publication-title: Pharmacol Toxicol
  contributor:
    fullname: Muraoka, S; Miura, T
– volume: 148
  start-page: 131
  year: 2000
  end-page: 9
  article-title: Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?
  publication-title: Atherosclerosis
  contributor:
    fullname: Nieto, FJ; Iribarren, C; Gross, MD; Comstock, GW; Cutler, RG
– volume: 38
  start-page: 1101
  year: 2001
  end-page: 6
  article-title: Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism
  publication-title: Hypertension
  contributor:
    fullname: Mazzali, M; Hughes, J; Kim, YG; Jefferson, JA; Kang, DH; Gordon, KL
– volume: 877
  start-page: 2032
  year: 2009
  end-page: 8
  article-title: A sensitive and specifc liquid chromatography tandem mass spectrometry method for the determination of intracellular and extracellular uric acid
  publication-title: J Chromatogr B Analyt Technol Biomed Life Sci
  contributor:
    fullname: Kim, KM; Henderson, GN; Ouyang, X; Frye, RF; Sautin, YY; Feig, DI
– volume: 7
  start-page: 461
  year: 2005
  end-page: 67
  article-title: The increase in serum uric acid concentration caused by diuretics might be beneficial in heart failure
  publication-title: Eur J Heart Fail
  contributor:
    fullname: Reyes, AJ
– volume: 79
  start-page: 967
  year: 1999
  end-page: 74
  article-title: Cellular expression of xanthine oxidoreductase protein in normal human tissues
  publication-title: Lab Invest
  contributor:
    fullname: Linder, N; Rapola, J; Raivio, KO
– volume: 25
  start-page: 1291
  year: 2006
  end-page: 4
  article-title: Purine catabolism in advanced carotid artery plaque
  publication-title: Nucleosides Nucleotides Nucleic acids
  contributor:
    fullname: Felici, C; Ciari, I; Terzuoli, L; Porcelli, B; Setacci, C; Giubbolini, M
– volume: 256
  start-page: 9090
  year: 1981
  end-page: 5
  article-title: Studies on the oxidative half reaction of xanthine oxidase
  publication-title: J Biol Chem
  contributor:
    fullname: Hille, R; Massey, V
– volume: 41
  start-page: 1287
  year: 2003
  end-page: 93
  article-title: Uric acid stimulates monocyte chemoattractant protein 1 production in vascular smooth muscle cells via mitogen activated protein kinase and cyclooxygenase-2
  publication-title: Hypertension
  contributor:
    fullname: Kanellis, J; Watanabe, S; Li, JH; Kang, DH; Li, P; Nakagawa, T
– volume: 25
  start-page: 3
  year: 2005
  end-page: 8
  article-title: Uric acid evolution and primitive cultures
  publication-title: Semin Nephrol
  contributor:
    fullname: Johnson, RJ; Titte, S; Cade, JR; Rideout, BA; Oliver, WJ
– volume: 104
  start-page: 2407
  year: 2001
  end-page: 11
  article-title: Allopurinol improves myocardial effciency in patients with idiopathic dilated cardiomyopathy
  publication-title: Circulation
  contributor:
    fullname: Cappola, TP; Kass, DA; Nelson, GS; Berger, RD; Rosas, GO; Kobeissi, ZA
– volume: 415
  start-page: 127
  year: 1989
  end-page: 35
  article-title: Uric acid as radical scavenger and antioxidant in the heart
  publication-title: Pfugers Arch
  contributor:
    fullname: Becker, BF; Reinholz, N; Ozcelik, T; Leipert, B; Gerlach, E
– volume: 93
  start-page: 903
  year: 2007
  end-page: 7
  article-title: Oxidative stress and redox signalling in cardiac hypertrophy and heart failure
  publication-title: Heart
  contributor:
    fullname: Seddon, M; Looi, YH; Shah, AM
– volume: 106
  start-page: 3073
  year: 2002
  end-page: 8
  article-title: Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase
  publication-title: Circulation
  contributor:
    fullname: Landmesser, U; Spiekermann, S; Dikalov, S; Tatge, H; Wilke, R; Kohler, C
– volume: 95
  start-page: 67
  year: 2006
  end-page: 75
  article-title: L-arginine attenuates xanthine oxidase and myeloperoxidase activities in hearts of rats during exhaustive exercise
  publication-title: Br J Nutr
  contributor:
    fullname: Lin, WT; Yang, SC; Tsai, SC; Huang, CC; Lee, NY
– volume: 116
  start-page: 1
  year: 1994
  end-page: 6
  article-title: The conversion of xanthine dehydrogenase to xanthine oxidase and the role of the enzyme in reperfusion injury
  publication-title: J Biochem
  contributor:
    fullname: Nishino, T
– volume: 279
  start-page: 52797
  year: 2004
  end-page: 805
  article-title: Signaling events involved in macrophage chemokine expression in response to monosodium urate crystals
  publication-title: J Biol Chem
  contributor:
    fullname: Jaramillo, M; Godbout, M; Naccache, PH; Olivier, M
– volume: 45
  start-page: 363
  year: 2009
  end-page: 78
  article-title: Allopurinol an inhibitor of uric acid synthesiscan it be used for the treatment of metabolic syndrome and related disorders?
  publication-title: Drugs Today Barc
  contributor:
    fullname: Suzuki, I; Yamauchi, T; Onuma, M; Nozaki, S
– volume: 21
  start-page: 610
  year: 2007
  end-page: 5
  article-title: Serum uric acid is associated with microvascular function in hypertensive individuals
  publication-title: J Hum Hypertens
  contributor:
    fullname: De, AC; Turner, ST; Kullo, IJ
– volume: 105
  start-page: 2619
  year: 2002
  end-page: 24
  article-title: Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood fow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies
  publication-title: Circulation
  contributor:
    fullname: Doehner, W; Schoene, N; Rauchhaus, M; Leyva-León, F; Pavitt, DV; Reaveley, DA
– volume: 10
  start-page: 1269
  year: 2008
  end-page: 70
  article-title: Uric acid in chronic heart failure current pathophysiological concepts
  publication-title: Eur J Heart Fail
  contributor:
    fullname: Doehner, W; Springer, J; Landmesser, U; Struthers, AD; Anker, SD
– volume: 22
  start-page: 209
  year: 1997
  end-page: 14
  article-title: Urate protects a blood-sucking insect against hemin-induced oxidative stress
  publication-title: Free Radic Biol Med
  contributor:
    fullname: Souza, AV; Petretski, JH; Demasi, M; Bechara, EJ; Oliveira, PL
– volume: 10
  start-page: 646
  year: 2008
  end-page: 51
  article-title: Serum uric acid correlates with ex-tracellular superoxide dismutase activity in patients with chronic heart failure
  publication-title: Eur J Heart Fail
  contributor:
    fullname: Alcaíno, H; Greig, D; Chiong, M; Verdejo, H; Miranda, R; Concepción, R
– volume: 69
  start-page: 720
  year: 2002
  article-title: The crystal the gout and the paradox
  publication-title: Cleve Clin J Med
  contributor:
    fullname: Mandell, BF
– volume: 19
  start-page: 96
  year: 2005
  end-page: 100
  article-title: Ascorbic acid and uric acid suppress glucose induced fibronectin and vascular endothelial growth factor production in human endothelial cells
  publication-title: J Diabetes complications
  contributor:
    fullname: Hsu, CC; Yin, MC; Tian, R
– volume: 392
  start-page: 1
  year: 2008
  end-page: 7
  article-title: The paradoxical relationship between serum uric acid and cardiovascular disease
  publication-title: Clin Chim Acta
  contributor:
    fullname: Lippi, G; Montagnana, M; Franchini, M; Favaloro, EJ; Targher, G
– volume: 16
  start-page: 485
  year: 2002
  end-page: 7
  article-title: The ALLHAT and the cardioprotection conferred by diuretics in hypertensive patients: a connection with uric acid?
  publication-title: Cardiovasc Drugs Ther
  contributor:
    fullname: Reyes, AJ; Leary, WP
– volume: 33
  start-page: 1363
  year: 2002
  end-page: 71
  article-title: Comparison of uric acid and ascorbic acid in protection against EAE
  publication-title: Free Radic Biol Med
  contributor:
    fullname: Spitsin, SV; Scott, GS; Mikheeva, T; Zborek, A; Kean, RB; Brimer, CM
– volume: 106
  start-page: 221
  year: 2002
  end-page: 6
  article-title: Allopurinol improves endothelial dysfunction in chronic heart failure
  publication-title: Circulation
  contributor:
    fullname: Farquharson, CA; Butler, R; Hill, A; Belch, JJ; Struthers, AD
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Title Ácido úrico: una molécula con acciones paradójicas en la insuficiencia cardiaca
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