Sodium dithionite mediated one-pot, tandem chemoselective reduction/cyclization for the synthesis of pyrrole fused N -heterocycles

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 25; no. 1; pp. 161 - 166
• Main Authors: Laha, Joydev K., Panday, Surabhi, Gupta, Pankaj, Seth, Shiv Raj
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 03.01.2023; Royal Society of Chemistry
• Subjects: Aldehydes; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Crystallization; Dithionite; Functional groups; Green & Sustainable Science & Technology; Green chemistry; Physical Sciences; Quinoxalines; Reaction time; Reagents; Reduction; Room temperature; Science & Technology; Science & Technology - Other Topics; Sodium; Sodium dithionite; Substrates; 2-FORMYLAZOLES; REDUCTION; AMINES; ACIDS; STRATEGY; EFFICIENT SYNTHESIS; INHIBITORS; CLEAVAGE; DERIVATIVES; COPPER-CATALYZED ANNULATION

A chemoselective reduction of a nitro group in the presence of an aldehyde or ester group integrated with another synthetic transformation leading to the expedient synthesis of important heterocycles is the subject of this current investigation. The chemoselective reductive cyclization of N -(2-nitr...