Mechanism and Clinical Application of PD-1/PD-L1 Inhibitors in Immunotherapy

Tumor immunotherapy is currently a hot research topic in the field of oncology, and is an efficacious mode of tumor treatment. Programmed cell death receptor PD-1 (PD-1) is an important immunosuppressive molecule, which is mainly expressed in activated T and B cells. PD-1/PD-L1 inhibitors can block...

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Published inBIO web of conferences Vol. 55; p. 1007
Main Author Yang, Xicheng
Format Journal Article
LanguageEnglish
Published EDP Sciences 01.01.2022
Subjects
immunosuppressive molecules
pd-1/pd-l1. tumor immunotherapy
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Abstract Tumor immunotherapy is currently a hot research topic in the field of oncology, and is an efficacious mode of tumor treatment. Programmed cell death receptor PD-1 (PD-1) is an important immunosuppressive molecule, which is mainly expressed in activated T and B cells. PD-1/PD-L1 inhibitors can block the binding of PD-1 to PD-L1, block the negative regulatory signals, and restore the activity of T cells, thus enhancing the immune response.
AbstractList Tumor immunotherapy is currently a hot research topic in the field of oncology, and is an efficacious mode of tumor treatment. Programmed cell death receptor PD-1 (PD-1) is an important immunosuppressive molecule, which is mainly expressed in activated T and B cells. PD-1/PD-L1 inhibitors can block the binding of PD-1 to PD-L1, block the negative regulatory signals, and restore the activity of T cells, thus enhancing the immune response.
Author Yang, Xicheng
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Snippet Tumor immunotherapy is currently a hot research topic in the field of oncology, and is an efficacious mode of tumor treatment. Programmed cell death receptor...
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SubjectTerms immunosuppressive molecules
pd-1/pd-l1. tumor immunotherapy
Title Mechanism and Clinical Application of PD-1/PD-L1 Inhibitors in Immunotherapy
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