Occurrence and trends of Clostridioides difficile infections in hospitalized patients: a prospective multi-centre cohort study in six German university hospitals, 2016–2020

• Published in: The Journal of hospital infection Vol. 151; pp. 161 - 172
• Main Authors: Jazmati, N., Mischnik, A., Kern, W.V., Behnke, M., Chakraborty, T., Dinkelacker, A., Eisenbeis, S., Falgenhauer, J., Gastmeier, P., Häcker, G., Imirzalioglu, C., Käding, N., Kramme, E., Peter, S., Piepenbrock, E., Rupp, J., Schneider, C., Schwab, F., Seifert, H., Tacconelli, E., Trauth, J., Biehl, L., Walker, S.V., Rohde, A.M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2024
• Subjects: Adult; Aged; Aged, 80 and over; Clostridioides difficile; Clostridium Infections - epidemiology; Cross Infection - epidemiology; Epidemiology; Female; Germany; Germany - epidemiology; Hospitals, University - statistics & numerical data; Humans; Incidence; Infection; Length of Stay - statistics & numerical data; Male; Middle Aged; Prospective Studies; Risk Factors; Germany; Infection; Clostridioides difficile; Epidemiology; Germany; Incidence

For Clostridioides difficile infections (CDIs) in Germany no longitudinal multi-centre studies with standardized protocols for diagnosing CDI are available. Recent evaluations of general surveillance databases in Germany indicate a downward trend in CDI rates. We aimed to describe the actual burden...