Lower synaptic density associated with gaming disorder: an 18 F-SynVesT-1 PET imaging study

• Published in: General psychiatry Vol. 36; no. 5; p. e101112
• Main Authors: Hou, Jiale, Xiao, Qian, Zhou, Ming, Xiao, Ling, Yuan, Ming, Zhong, Na, Long, Jiang, Luo, Tao, Hu, Shuo, Dong, Huixi
• Format: Journal Article
• Language: English
• Published: England 10.10.2023
• Subjects: Behavior, Addictive; Cognition; Adolescent Behavior; Adolescent Psychiatry

Internet gaming disorder (IGD) is an ideal model to study the mechanisms underlying synaptic deficits in addiction as it eliminates the confounding effects of substance use. Synaptic loss and deficits are hypothesised to underlie the enduring maladaptive behaviours and impaired cognitive function th...