In Silico Dose Adjustment of Zolpidem in Females Using Physiologically Based Pharmacokinetic Modeling and Simulations - Malayandi, Rajkumar; Karmakar, Arka; Dhake, Pratik; Malgave, Adarsh; Natesan, Subramanian; Velayutham, Ravichandiran (Sleep and vigilance, 2024)
Keywords: Benzodiazepines; Bioavailability; Biomedical and Life Sciences; Biomedicine; Clinical outcomes; Drug dosages; Enzymes; FDA approval; Females; Gender differences; Insomnia; Males; Medicine/Public Health; Metabolism; Metabolites; Molecular weight; Neurology; Neurosciences; Original Article; Particle size; Permeability; Pharmacokinetics; Plasma; Product development; Psychiatry; Simulation; Women; Virtual bioequivalence; Zolpidem; PBPK; Dose adjustment; Pharmacokinetics; Sex difference