DOFETILIDE EFFICACY AND SAFETY PROFILE IN OFF-LABEL USE

Dofetilide was discontinued in 20 patients (15%) during the initiation admission and in 21 patients (16%) within 6 weeks of initiation (24 due to inefficacy, 9 with excessive QT prolongation, 4 with Torsades de Pointes, 3 unable to afford the medication, and 1 with worsening renal function).

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Published inJournal of the American College of Cardiology Vol. 59; no. 13; p. E683
Main Authors Brumberg, Genevieve E, Gera, Nitin, Adelstein, Evan, Saba, Samir, Jain, Sandeep
Format Journal Article
LanguageEnglish
Published New York Elsevier Inc 27.03.2012
Elsevier Limited
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Abstract Dofetilide was discontinued in 20 patients (15%) during the initiation admission and in 21 patients (16%) within 6 weeks of initiation (24 due to inefficacy, 9 with excessive QT prolongation, 4 with Torsades de Pointes, 3 unable to afford the medication, and 1 with worsening renal function).
AbstractList Dofetilide was discontinued in 20 patients (15%) during the initiation admission and in 21 patients (16%) within 6 weeks of initiation (24 due to inefficacy, 9 with excessive QT prolongation, 4 with Torsades de Pointes, 3 unable to afford the medication, and 1 with worsening renal function).
Author Adelstein, Evan
Jain, Sandeep
Gera, Nitin
Saba, Samir
Brumberg, Genevieve E
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Copyright American College of Cardiology Foundation
2012 American College of Cardiology Foundation
Copyright Elsevier Limited Mar 27, 2012
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Snippet Dofetilide was discontinued in 20 patients (15%) during the initiation admission and in 21 patients (16%) within 6 weeks of initiation (24 due to inefficacy, 9...
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StartPage E683
SubjectTerms Cardiac arrhythmia
Cardiology
Cardiovascular
Drug therapy
Internal Medicine
Medical research
Title DOFETILIDE EFFICACY AND SAFETY PROFILE IN OFF-LABEL USE
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