Synthesis, photophysical and cytotoxicity evaluation of A3B type mesoporphyrinic compounds

A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were characterized by elemental analysis, FT-IR, UV–Vis, NMR and EPR spectroscopy, which fully confirmed their structures. The spectral molecular absorpti...

Full description

Saved in:
Bibliographic Details
Published inDyes and pigments Vol. 95; no. 2; pp. 296 - 303
Main Authors Vieira Ferreira, Luís F., Ferreira, Diana P., Oliveira, Anabela S., Boscencu, Rica, Socoteanu, Radu, Ilie, Mihaela, Constantin, Carolina, Neagu, Monica
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.11.2012
Subjects
Online AccessGet full text

Cover

Loading…
Abstract A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were characterized by elemental analysis, FT-IR, UV–Vis, NMR and EPR spectroscopy, which fully confirmed their structures. The spectral molecular absorption properties of the porphyrinic compounds were studied in different solvents and the influence of the solvent polarity on the absorbance maxima was described. Fluorescence emission and singlet oxygen formation quantum yields were evaluated for A3B type mesoporphyrinic compounds and compared with the corresponding symmetrical compounds, revealing high yields for the metal free compounds, followed by the zinc derivatives. The copper mesoporphyrinic compounds are not emissive and only evidence residual capacity for singlet oxygen formation. In order to establish their future potential in biomedical application preliminary toxicological studies, consisting of viability and proliferation of living cells in the presence of the unsymmetrical mesoporphyrinic compounds, were performed in the dark, on a standard cell line of human Caucasian histiocytic lymphoma (U937). The obtained results indicate a very low or no cytotoxicity at all for all compounds under study. Therefore further testing with light activation protocols is recommended in future work. [Display omitted] ► Novel unsymmetrical mesoporphyrins were obtained via microwave assisted synthesis. ► Free basis and zinc porphyrins revealed high fluorescence quantum yields. ► Singlet oxygen formation quantum yields had similar pattern indicating them for PDT. ► Compounds showed no dark toxicity and a slight inhibition of the cell proliferation.
AbstractList A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were characterized by elemental analysis, FT-IR, UV-Vis, NMR and EPR spectroscopy, which fully confirmed their structures. The spectral molecular absorption properties of the porphyrinic compounds were studied in different solvents and the influence of the solvent polarity on the absorbance maxima was described. Fluorescence emission and singlet oxygen formation quantum yields were evaluated for A3B type mesoporphyrinic compounds and compared with the corresponding symmetrical compounds, revealing high yields for the metal free compounds, followed by the zinc derivatives. The copper mesoporphyrinic compounds are not emissive and only evidence residual capacity for singlet oxygen formation. In order to establish their future potential in biomedical application preliminary toxicological studies, consisting of viability and proliferation of living cells in the presence of the unsymmetrical mesoporphyrinic compounds, were performed in the dark, on a standard cell line of human Caucasian histiocytic lymphoma (U937). The obtained results indicate a very low or no cytotoxicity at all for all compounds under study. Therefore further testing with light activation protocols is recommended in future work.
A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were characterized by elemental analysis, FT-IR, UV–Vis, NMR and EPR spectroscopy, which fully confirmed their structures. The spectral molecular absorption properties of the porphyrinic compounds were studied in different solvents and the influence of the solvent polarity on the absorbance maxima was described. Fluorescence emission and singlet oxygen formation quantum yields were evaluated for A3B type mesoporphyrinic compounds and compared with the corresponding symmetrical compounds, revealing high yields for the metal free compounds, followed by the zinc derivatives. The copper mesoporphyrinic compounds are not emissive and only evidence residual capacity for singlet oxygen formation. In order to establish their future potential in biomedical application preliminary toxicological studies, consisting of viability and proliferation of living cells in the presence of the unsymmetrical mesoporphyrinic compounds, were performed in the dark, on a standard cell line of human Caucasian histiocytic lymphoma (U937). The obtained results indicate a very low or no cytotoxicity at all for all compounds under study. Therefore further testing with light activation protocols is recommended in future work. [Display omitted] ► Novel unsymmetrical mesoporphyrins were obtained via microwave assisted synthesis. ► Free basis and zinc porphyrins revealed high fluorescence quantum yields. ► Singlet oxygen formation quantum yields had similar pattern indicating them for PDT. ► Compounds showed no dark toxicity and a slight inhibition of the cell proliferation.
Author Ilie, Mihaela
Oliveira, Anabela S.
Socoteanu, Radu
Ferreira, Diana P.
Constantin, Carolina
Neagu, Monica
Boscencu, Rica
Vieira Ferreira, Luís F.
Author_xml – sequence: 1
  givenname: Luís F.
  surname: Vieira Ferreira
  fullname: Vieira Ferreira, Luís F.
  email: luisfilipevf@ist.utl.pt
  organization: Centro de Química-Física Molecular, Institute of Nanosciences and Nanotechnology, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
– sequence: 2
  givenname: Diana P.
  surname: Ferreira
  fullname: Ferreira, Diana P.
  email: diana.ferreira@ist.utl.pt
  organization: Centro de Química-Física Molecular, Institute of Nanosciences and Nanotechnology, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
– sequence: 3
  givenname: Anabela S.
  surname: Oliveira
  fullname: Oliveira, Anabela S.
  email: asoliveira@ist.utl.pt
  organization: Centro de Química-Física Molecular, Institute of Nanosciences and Nanotechnology, Instituto Superior Técnico, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
– sequence: 4
  givenname: Rica
  surname: Boscencu
  fullname: Boscencu, Rica
  email: rboscencu@yahoo.com
  organization: Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia St., 020956 Bucharest, Romania
– sequence: 5
  givenname: Radu
  surname: Socoteanu
  fullname: Socoteanu, Radu
  email: psradu@yahoo.com
  organization: “Ilie Murgulescu” Institute of Physical Chemistry, Romanian Academy, 202 Splaiul Independentei, 060021 Bucharest, Romania
– sequence: 6
  givenname: Mihaela
  surname: Ilie
  fullname: Ilie, Mihaela
  email: m16ilie@yahoo.com
  organization: Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia St., 020956 Bucharest, Romania
– sequence: 7
  givenname: Carolina
  surname: Constantin
  fullname: Constantin, Carolina
  email: caroconstantin@yahoo.com
  organization: “Victor Babeş” National Institute for Pathology and Biomedical Sciences, 99-101 Splaiul Independentei, 050096 Bucharest, Romania
– sequence: 8
  givenname: Monica
  surname: Neagu
  fullname: Neagu, Monica
  email: neagu.monica@gmail.com
  organization: “Victor Babeş” National Institute for Pathology and Biomedical Sciences, 99-101 Splaiul Independentei, 050096 Bucharest, Romania
BookMark eNp9kDtPwzAUhS1UJErhHzB4ZCDBj6RxFqRS8ZIqMQALi2U7N9RVYgc7qci_J1WZmT7p6pxPuucczZx3gNAVJSkldHm7S6sROvuVMkJZSvJ0wgmaU1HwhBcZn6E5oRlPCkbEGTqPcUcIEZzROfp8G12_hWjjDe62vvfddozWqAYrV2Ez9tPpxxrbjxj2qhlUb73DvsYrfo_7sQPcQvSdD1MvWGcNNr7t_OCqeIFOa9VEuPzjAn08Pryvn5PN69PLerVJDBVZmWhNtS4LowQreVUVHJimpag0IRljBSgBmmd5XWvgNSmBcgFC14xmSqu8LPkCXR-9XfDfA8RetjYaaBrlwA9R0mVBMzqpDtHsGDXBxxigll2wrQqjpEQeppQ7eZxSHqaUJJcTptrdsQbTG3sLQUZjwRmobADTy8rb_wW_FM-CwA
CitedBy_id crossref_primary_10_1016_j_dyepig_2018_08_028
crossref_primary_10_1080_00958972_2014_915966
crossref_primary_10_1016_j_ijbiomac_2024_132579
crossref_primary_10_1111_jcmm_14009
crossref_primary_10_1039_c3pp50132a
crossref_primary_10_1016_j_tet_2014_12_048
crossref_primary_10_1039_C5NJ02888D
crossref_primary_10_3390_molecules28031149
crossref_primary_10_1016_j_ccr_2024_215661
crossref_primary_10_1016_j_chemphys_2021_111115
crossref_primary_10_1016_j_jphotochem_2019_112152
crossref_primary_10_3390_molecules200915488
crossref_primary_10_3390_ph17010062
crossref_primary_10_1080_1062936X_2020_1747534
crossref_primary_10_18632_oncotarget_11942
crossref_primary_10_1016_j_mseb_2019_05_012
crossref_primary_10_1134_S1070428022040017
crossref_primary_10_1016_j_carbpol_2016_05_060
crossref_primary_10_1016_j_jphotochemrev_2020_100401
crossref_primary_10_1039_C5CP04359J
crossref_primary_10_3390_molecules22111815
Cites_doi 10.3390/molecules15053731
10.1016/j.addr.2008.08.003
10.1016/j.jaad.2009.09.056
10.1021/jp0520087
10.1016/S1010-6030(96)04371-7
10.1016/j.cbpa.2009.09.029
10.1016/S0898-8838(09)00203-7
10.1016/j.tripleo.2009.10.006
10.1016/j.jaad.2009.09.057
10.1016/S1011-1344(00)00082-8
10.1016/j.pdpdt.2010.02.001
10.1039/b315586b
10.1002/lsm.20352
10.1039/B212890J
10.1016/0005-2736(91)90008-V
10.1016/B978-0-12-220103-5.50008-8
10.1016/j.freeradbiomed.2010.05.027
10.1016/j.biocel.2004.06.013
10.1111/j.1751-1097.1996.tb03093.x
10.1016/0022-1759(83)90438-6
10.1016/S1470-2045(04)01529-3
10.1016/j.ijpharm.2007.06.019
10.1016/j.canlet.2005.12.041
10.1111/j.1365-2818.2005.01471.x
10.2298/JSC0807713B
10.1016/1011-1344(95)07155-U
10.1016/j.jphotobiol.2006.03.006
10.1016/0022-2852(74)90263-X
10.1016/S0960-894X(01)81162-8
10.1016/B978-012513910-6/50026-8
10.1021/jm040074b
ContentType Journal Article
Copyright 2012 Elsevier Ltd
Copyright_xml – notice: 2012 Elsevier Ltd
DBID AAYXX
CITATION
7QQ
8FD
JG9
DOI 10.1016/j.dyepig.2012.05.012
DatabaseName CrossRef
Ceramic Abstracts
Technology Research Database
Materials Research Database
DatabaseTitle CrossRef
Materials Research Database
Technology Research Database
Ceramic Abstracts
DatabaseTitleList Materials Research Database

DeliveryMethod fulltext_linktorsrc
Discipline Engineering
Chemistry
Physics
EISSN 1873-3743
EndPage 303
ExternalDocumentID 10_1016_j_dyepig_2012_05_012
S0143720812001416
GroupedDBID --K
--M
.-4
.~1
0R~
1B1
1~.
1~5
29G
4.4
457
4G.
5GY
5VS
7-5
71M
8P~
9JN
AABNK
AABXZ
AACTN
AAEDT
AAEDW
AAEPC
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AAXUO
ABFNM
ABJNI
ABMAC
ABNUV
ABXDB
ABXRA
ABYKQ
ACDAQ
ACGFS
ACNNM
ACRLP
ADBBV
ADEWK
ADEZE
ADMUD
AEBSH
AECPX
AEKER
AENEX
AEZYN
AFKWA
AFRZQ
AFTJW
AGHFR
AGUBO
AGYEJ
AHHHB
AHPOS
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
AKURH
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BBWZM
BKOJK
BLXMC
CS3
DU5
EBS
EFJIC
EFLBG
EJD
ENUVR
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
G8K
GBLVA
HLY
HVGLF
HZ~
IHE
J1W
JJJVA
KOM
LX7
M24
M41
MAGPM
MO0
N9A
NDZJH
O-L
O9-
OAUVE
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
RNS
ROL
RPZ
SCE
SDF
SDG
SDP
SES
SEW
SMS
SPC
SPCBC
SSG
SSM
SSZ
T5K
UHS
WH7
WUQ
XPP
~G-
AAXKI
AAYXX
ABDPE
ACRPL
ADNMO
AFJKZ
AKRWK
CITATION
7QQ
8FD
JG9
ID FETCH-LOGICAL-c1849-bb1bb97ca8293dd73e2b198db004227ea8eb345ffbe3f09e138e8bf214aba5993
IEDL.DBID AIKHN
ISSN 0143-7208
IngestDate Fri Oct 25 08:38:41 EDT 2024
Fri Dec 06 01:00:53 EST 2024
Fri Feb 23 02:22:38 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords Fluorescence
Cytotoxicity
Singlet oxygen
Unsymmetrical mesoporphyrins
Language English
License https://www.elsevier.com/tdm/userlicense/1.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c1849-bb1bb97ca8293dd73e2b198db004227ea8eb345ffbe3f09e138e8bf214aba5993
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
PQID 1671412279
PQPubID 23500
PageCount 8
ParticipantIDs proquest_miscellaneous_1671412279
crossref_primary_10_1016_j_dyepig_2012_05_012
elsevier_sciencedirect_doi_10_1016_j_dyepig_2012_05_012
PublicationCentury 2000
PublicationDate November 2012
2012-11-00
20121101
PublicationDateYYYYMMDD 2012-11-01
PublicationDate_xml – month: 11
  year: 2012
  text: November 2012
PublicationDecade 2010
PublicationTitle Dyes and pigments
PublicationYear 2012
Publisher Elsevier Ltd
Publisher_xml – name: Elsevier Ltd
References Milgrom (bib40) 1997
Boyle, Dolphin (bib21) 1996; 64
Lin (bib33) 1978
Stolik, Delgado, Pérez, Anasagasti (bib20) 2000; 57
Hilderbrand, Weissleder (bib3) 2010; 14
Botelho do Rego, Vieira Ferreira (bib32) 2001
Riccheli (bib26) 1995; 29
Chatterjee, Yong (bib4) 2008; 60
Sakamoto, Lopes, Anderson (bib9) 2010; 63
Sakamoto, Torezan, Anderson (bib10) 2010; 63
Ricchelli, Jori, Gobbo, Tronchin (bib23) 1991; 1065
Socoteanu, Boscencu, Nacea, Oliveira, Vieira Ferreira (bib28) 2008; 59
Gouterman, Khalil (bib39) 1974; 53
Rechmond, Braslavsky (bib38) 1988; 15
Berg, Selbo, Weyergang, Dietze, Prasmickaite, Bonsted (bib7) 2005; 218
Zhenyu, Yang, Vasovic, Cunderlikova, Suo, Nesland (bib27) 2006; 84
Boscencu, Socoteanu, Oliveira, Vieira Ferreira (bib17) 2008; 73
Boscencu, Ilie, Socoteanu, Oliveira, Constantin, Neagu (bib15) 2010; 15
de Oliveira Mima, Pavarina, Dovigo, Vergani, de Souza Costa, Kurachi (bib11) 2010; 109
Chin, O.Lau, Bhuvaneswari, Heng, Olivo (bib6) 2007; 245
Jori, Schind, Schind, Polo (bib19) 1996; 102
Barltrop, Owen, Cory, Cory (bib30) 1991; 1
Boscencu, Socoteanu, Ilie, Sousa Oliveira, Constantin, Vieira Ferreira (bib14) 2009; 60
Milanesio, Alvarez, Silber, Rivarola, Durantini (bib24) 2003; 2
Branco, Botelho do Rego, Ferreira Machado, Vieira Ferreira (bib31) 2005; 109
Gouterman (bib36) 1978
Ramaswamy, Manivasager, Chin, Soo, Olivo (bib8) 2005; 26
Riccheli, Franchi, Miotto, Borsetto, Gobbo, Nicolov (bib25) 2005; 37
Pascu, Waghorn, Conry, Lin, James, Zayed (bib22) 2009; 61
Kamuhabwa, Agostinis, Ahmed, Landuyt, Van Cleynenbreugel, Van Poppel (bib2) 2004; 3
Detty, Gibson, Wagner (bib1) 2004; 47
Chin, Lau, Cheng, Olivo (bib13) 2004; 25
Ragàs, Agut, Nonell (bib12) 2010; 49
Boscencu, Licsandru, Socoteanu, Oliveira, Vieira Ferreira (bib18) 2007; 58
Kivelson, Neiman (bib35) 1961; 35
Manoharan, Roger (bib34) 1969
Korzeniewski, Callewaert (bib29) 1983; 64
Bonneau, Bizet, Mojzisova, Brault (bib5) 2007; 344
Boscencu, Socoteanu, Oliveira, Vieira Ferreira, Nacea, Patrinoiu (bib16) 2008; 82
Brown, Brown, Walker (bib41) 2004; 5
Rendel (bib37) 1987
Pandey, Goswami, Chen, Gryshuk, Missert, Oseroff (bib43) 2006; 38
Allison, Sibata (bib42) 2010; 7
Botelho do Rego (10.1016/j.dyepig.2012.05.012_bib32) 2001
Ricchelli (10.1016/j.dyepig.2012.05.012_bib23) 1991; 1065
Boyle (10.1016/j.dyepig.2012.05.012_bib21) 1996; 64
Manoharan (10.1016/j.dyepig.2012.05.012_bib34) 1969
Rechmond (10.1016/j.dyepig.2012.05.012_bib38) 1988; 15
de Oliveira Mima (10.1016/j.dyepig.2012.05.012_bib11) 2010; 109
Detty (10.1016/j.dyepig.2012.05.012_bib1) 2004; 47
Chin (10.1016/j.dyepig.2012.05.012_bib13) 2004; 25
Chin (10.1016/j.dyepig.2012.05.012_bib6) 2007; 245
Lin (10.1016/j.dyepig.2012.05.012_bib33) 1978
Allison (10.1016/j.dyepig.2012.05.012_bib42) 2010; 7
Jori (10.1016/j.dyepig.2012.05.012_bib19) 1996; 102
Boscencu (10.1016/j.dyepig.2012.05.012_bib15) 2010; 15
Socoteanu (10.1016/j.dyepig.2012.05.012_bib28) 2008; 59
Gouterman (10.1016/j.dyepig.2012.05.012_bib36) 1978
Riccheli (10.1016/j.dyepig.2012.05.012_bib25) 2005; 37
Boscencu (10.1016/j.dyepig.2012.05.012_bib18) 2007; 58
Milanesio (10.1016/j.dyepig.2012.05.012_bib24) 2003; 2
Stolik (10.1016/j.dyepig.2012.05.012_bib20) 2000; 57
Hilderbrand (10.1016/j.dyepig.2012.05.012_bib3) 2010; 14
Chatterjee (10.1016/j.dyepig.2012.05.012_bib4) 2008; 60
Riccheli (10.1016/j.dyepig.2012.05.012_bib26) 1995; 29
Kamuhabwa (10.1016/j.dyepig.2012.05.012_bib2) 2004; 3
Sakamoto (10.1016/j.dyepig.2012.05.012_bib9) 2010; 63
Korzeniewski (10.1016/j.dyepig.2012.05.012_bib29) 1983; 64
Barltrop (10.1016/j.dyepig.2012.05.012_bib30) 1991; 1
Rag?s (10.1016/j.dyepig.2012.05.012_bib12) 2010; 49
Berg (10.1016/j.dyepig.2012.05.012_bib7) 2005; 218
Ramaswamy (10.1016/j.dyepig.2012.05.012_bib8) 2005; 26
Sakamoto (10.1016/j.dyepig.2012.05.012_bib10) 2010; 63
Pandey (10.1016/j.dyepig.2012.05.012_bib43) 2006; 38
Bonneau (10.1016/j.dyepig.2012.05.012_bib5) 2007; 344
Boscencu (10.1016/j.dyepig.2012.05.012_bib16) 2008; 82
Milgrom (10.1016/j.dyepig.2012.05.012_bib40) 1997
Pascu (10.1016/j.dyepig.2012.05.012_bib22) 2009; 61
Kivelson (10.1016/j.dyepig.2012.05.012_bib35) 1961; 35
Boscencu (10.1016/j.dyepig.2012.05.012_bib17) 2008; 73
Branco (10.1016/j.dyepig.2012.05.012_bib31) 2005; 109
Rendel (10.1016/j.dyepig.2012.05.012_bib37) 1987
Zhenyu (10.1016/j.dyepig.2012.05.012_bib27) 2006; 84
Brown (10.1016/j.dyepig.2012.05.012_bib41) 2004; 5
Boscencu (10.1016/j.dyepig.2012.05.012_bib14) 2009; 60
Gouterman (10.1016/j.dyepig.2012.05.012_bib39) 1974; 53
References_xml – volume: 49
  start-page: 770
  year: 2010
  end-page: 776
  ident: bib12
  article-title: Singlet oxygen in Escherichia coli: new insights for antimicrobial photodynamic therapy
  publication-title: Free Radic Biol Med
  contributor:
    fullname: Nonell
– volume: 35
  start-page: 149
  year: 1961
  end-page: 155
  ident: bib35
  article-title: ESR studies on the bonding in copper complexes
  publication-title: J Chem Phys
  contributor:
    fullname: Neiman
– volume: 15
  start-page: 93
  year: 1988
  end-page: 95
  ident: bib38
  article-title: NATO ASI Ser
  publication-title: Ser H
  contributor:
    fullname: Braslavsky
– volume: 2
  start-page: 926
  year: 2003
  end-page: 933
  ident: bib24
  article-title: Photodynamic activity of monocationic and no-charged methoxyphenylporphyrin derivatives in homogeneous and biological media
  publication-title: Photochem Photobiol Sci
  contributor:
    fullname: Durantini
– volume: 38
  start-page: 445
  year: 2006
  end-page: 467
  ident: bib43
  article-title: Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy
  publication-title: Lasers Surg Med
  contributor:
    fullname: Oseroff
– volume: 47
  start-page: 3897
  year: 2004
  end-page: 3915
  ident: bib1
  article-title: Current clinical and Preclinical photosensitizers for use in photodynamic therapy
  publication-title: J Med Chem
  contributor:
    fullname: Wagner
– volume: 245
  start-page: 127
  year: 2007
  end-page: 133
  ident: bib6
  article-title: Chlorin e6-polyvinylpyrrolidone as a fluorescent marker for fluorescence diagnosis of human bladder cancer implanted on the chick chorioallantoic membrane model
  publication-title: Cancer Lett
  contributor:
    fullname: Olivo
– volume: 1
  start-page: 611
  year: 1991
  end-page: 614
  ident: bib30
  article-title: 5-(3-carboxymethoxyphenyl)-2-(4,5- dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans as cell-viability indicators
  publication-title: Bioorg Med Chem Lett
  contributor:
    fullname: Cory
– year: 1997
  ident: bib40
  article-title: The colours of life
  contributor:
    fullname: Milgrom
– volume: 15
  start-page: 3731
  year: 2010
  end-page: 3743
  ident: bib15
  article-title: Microwave synthesis, basic spectral and biological evaluation of some copper (II) mesoporphyrinic complexes
  publication-title: Molecules
  contributor:
    fullname: Neagu
– volume: 63
  start-page: 195
  year: 2010
  end-page: 211
  ident: bib10
  article-title: Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice Part II. Understanding parameters for acne treatment with photodynamic therapy
  publication-title: J Am Acad Dermatol
  contributor:
    fullname: Anderson
– volume: 102
  start-page: 101
  year: 1996
  end-page: 107
  ident: bib19
  article-title: Novel approaches towards a detailed control of the mechanism and efficiency of photosensitized processes in vivo
  publication-title: J Photochem Photobiol A: Chem
  contributor:
    fullname: Polo
– volume: 61
  start-page: 131
  year: 2009
  end-page: 178
  ident: bib22
  article-title: Design considerations towards simultaneously radiolabeled and fluorescent imaging probes incorporating metallic species
  publication-title: Adv Inorg Chem
  contributor:
    fullname: Zayed
– start-page: 358
  year: 1978
  ident: bib33
  article-title: Electron spin resonance and electronic structure of metalloporphyrins
  publication-title: The porphyrins
  contributor:
    fullname: Lin
– volume: 109
  start-page: 15958
  year: 2005
  end-page: 15967
  ident: bib31
  article-title: A luminescence lifetime distributions analysis in heterogeneous systems by the use of Excel’s Solver
  publication-title: J Phys Chem B
  contributor:
    fullname: Vieira Ferreira
– volume: 7
  start-page: 61
  year: 2010
  end-page: 75
  ident: bib42
  article-title: Oncologic photodynamic therapy photosensitizers: a clinical review
  publication-title: Photodiagnosis Photodyn Ther
  contributor:
    fullname: Sibata
– volume: 3
  start-page: 772
  year: 2004
  end-page: 780
  ident: bib2
  article-title: Ypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder
  publication-title: Photochem Photobiol Sci
  contributor:
    fullname: Van Poppel
– volume: 29
  start-page: 109
  year: 1995
  end-page: 118
  ident: bib26
  article-title: Photophysical properties of porphyrins in biological membranes
  publication-title: J Photochem Photobiol B: Biol
  contributor:
    fullname: Riccheli
– volume: 1065
  start-page: 42
  year: 1991
  end-page: 48
  ident: bib23
  article-title: Liposomes as models to study the distribution of porphyrins in cell membranes
  publication-title: Biochim Biophys Acta
  contributor:
    fullname: Tronchin
– volume: 14
  start-page: 71
  year: 2010
  end-page: 79
  ident: bib3
  article-title: Near-infrared fluorescence: application to
  publication-title: Curr Opin Chem Biol
  contributor:
    fullname: Weissleder
– volume: 64
  start-page: 469
  year: 1996
  end-page: 485
  ident: bib21
  article-title: Structure and biodistribution relationships of photodynamic sensitizers
  publication-title: Photochem Photobiol
  contributor:
    fullname: Dolphin
– volume: 25
  start-page: 623
  year: 2004
  end-page: 629
  ident: bib13
  article-title: Evaluation of hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: biodistribution, light dose and drug-light interval effects
  publication-title: Int J Oncol
  contributor:
    fullname: Olivo
– volume: 57
  start-page: 90
  year: 2000
  end-page: 93
  ident: bib20
  article-title: Measurement of the penetration depths of red and near infrared light in human “ex vivo” tissues
  publication-title: J Photochem Photobiol B
  contributor:
    fullname: Anasagasti
– start-page: 143
  year: 1969
  ident: bib34
  publication-title: Electron spin resonance of metal complexes
  contributor:
    fullname: Roger
– volume: 218
  start-page: 133
  year: 2005
  end-page: 147
  ident: bib7
  article-title: Porphyrin related photosensitizers for cancer imaging and therapeutic applications
  publication-title: J Microsc
  contributor:
    fullname: Bonsted
– volume: 63
  start-page: 183
  year: 2010
  end-page: 193
  ident: bib9
  article-title: Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice. Part I. Acne vulgaris: when and why consider photodynamic therapy?
  publication-title: J Am Acad Dermatol
  contributor:
    fullname: Anderson
– volume: 109
  start-page: 392
  year: 2010
  end-page: 401
  ident: bib11
  article-title: Susceptibility of
  publication-title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  contributor:
    fullname: Kurachi
– volume: 60
  start-page: 1627
  year: 2008
  end-page: 1637
  ident: bib4
  article-title: Nanoparticles in photodynamic therapy: an emerging paradigm
  publication-title: Adv Drug Deliv Rev
  contributor:
    fullname: Yong
– start-page: 1
  year: 1978
  end-page: 165
  ident: bib36
  article-title: Optical spectra and electronic structure of porphyrins and related rings
  publication-title: The porphyrins
  contributor:
    fullname: Gouterman
– volume: 37
  start-page: 306
  year: 2005
  end-page: 319
  ident: bib25
  article-title: Meso-substituted tetra-cationic porphyrins photosensitize the death of human fibrosarcoma cells via lysosomal targeting
  publication-title: Int J Biochem Cell Biol
  contributor:
    fullname: Nicolov
– volume: 26
  start-page: 1501
  year: 2005
  end-page: 1506
  ident: bib8
  article-title: Photodynamic diagnosis of a human nasopharyngeal carcinoma xenograft model using the novel chlorin e6 photosensitizer fotolon
  publication-title: Int J Oncol
  contributor:
    fullname: Olivo
– start-page: 275
  year: 2001
  end-page: 313
  ident: bib32
  article-title: Photonic and electronic spectroscopies for the characterization of organic surfaces and organic molecules adsorbed on surfaces
  publication-title: Handbook of surfaces and interfaces of materials
  contributor:
    fullname: Vieira Ferreira
– volume: 53
  start-page: 88
  year: 1974
  end-page: 100
  ident: bib39
  article-title: Porphyrin free base phosphorescence
  publication-title: J Mol Spectrosc
  contributor:
    fullname: Khalil
– volume: 64
  start-page: 313
  year: 1983
  end-page: 320
  ident: bib29
  article-title: An enzyme-release assay for natural cytotoxicity
  publication-title: J Immunol Meth
  contributor:
    fullname: Callewaert
– volume: 59
  start-page: 969
  year: 2008
  end-page: 972
  ident: bib28
  article-title: Microwave-assisted synthesis of unsymmetrical tetrapyrrolic compounds
  publication-title: Revista De Chim
  contributor:
    fullname: Vieira Ferreira
– volume: 73
  start-page: 713
  year: 2008
  end-page: 726
  ident: bib17
  article-title: Studies on Zn(II) Monohydroxyphenyl substituted mesoporphyrins synthesis and characterisation
  publication-title: J Serbian Chem Soc
  contributor:
    fullname: Vieira Ferreira
– year: 1987
  ident: bib37
  article-title: Fluorescence and posphorescence spectroscopy
  contributor:
    fullname: Rendel
– volume: 5
  start-page: 497
  year: 2004
  end-page: 508
  ident: bib41
  article-title: The present and future role of photodynamic therapy in cancer treatment
  publication-title: Lancet Oncol
  contributor:
    fullname: Walker
– volume: 58
  start-page: 498
  year: 2007
  end-page: 502
  ident: bib18
  article-title: Synthesis and spectral characterisation of some unsymmetrically substituted mesoporphyrinic compounds
  publication-title: Revista De Chim
  contributor:
    fullname: Vieira Ferreira
– volume: 84
  start-page: 213
  year: 2006
  end-page: 220
  ident: bib27
  article-title: Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines
  publication-title: J Photochem Photobiol B Biol
  contributor:
    fullname: Nesland
– volume: 344
  start-page: 78
  year: 2007
  end-page: 87
  ident: bib5
  article-title: Tetrapyrrole-photosensitizers vectorization and plasma LDL: a physic-chemical approach
  publication-title: Int J Pharm
  contributor:
    fullname: Brault
– volume: 60
  start-page: 1006
  year: 2009
  end-page: 1011
  ident: bib14
  article-title: Synthesis, spectral and biological evaluation of some mesoporphyrinic complexes of Zn(II)
  publication-title: Revista De Chim
  contributor:
    fullname: Vieira Ferreira
– volume: 82
  start-page: 509
  year: 2008
  end-page: 521
  ident: bib16
  article-title: Synthesis and characterisation of some new unsymmetrically-substituted mesoporphyrinic mono-hydroxyphenyl complexes of Cu(II)
  publication-title: Polish J Chem
  contributor:
    fullname: Patrinoiu
– volume: 15
  start-page: 3731
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib15
  article-title: Microwave synthesis, basic spectral and biological evaluation of some copper (II) mesoporphyrinic complexes
  publication-title: Molecules
  doi: 10.3390/molecules15053731
  contributor:
    fullname: Boscencu
– start-page: 143
  year: 1969
  ident: 10.1016/j.dyepig.2012.05.012_bib34
  contributor:
    fullname: Manoharan
– volume: 60
  start-page: 1627
  year: 2008
  ident: 10.1016/j.dyepig.2012.05.012_bib4
  article-title: Nanoparticles in photodynamic therapy: an emerging paradigm
  publication-title: Adv Drug Deliv Rev
  doi: 10.1016/j.addr.2008.08.003
  contributor:
    fullname: Chatterjee
– year: 1997
  ident: 10.1016/j.dyepig.2012.05.012_bib40
  contributor:
    fullname: Milgrom
– volume: 63
  start-page: 183
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib9
  article-title: Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice. Part I. Acne vulgaris: when and why consider photodynamic therapy?
  publication-title: J?Am Acad Dermatol
  doi: 10.1016/j.jaad.2009.09.056
  contributor:
    fullname: Sakamoto
– volume: 109
  start-page: 15958
  year: 2005
  ident: 10.1016/j.dyepig.2012.05.012_bib31
  article-title: A?luminescence lifetime distributions analysis in heterogeneous systems by the use of Excel?s Solver
  publication-title: J?Phys Chem B
  doi: 10.1021/jp0520087
  contributor:
    fullname: Branco
– year: 1987
  ident: 10.1016/j.dyepig.2012.05.012_bib37
  contributor:
    fullname: Rendel
– volume: 102
  start-page: 101
  year: 1996
  ident: 10.1016/j.dyepig.2012.05.012_bib19
  article-title: Novel approaches towards a detailed control of the mechanism and efficiency of photosensitized processes in?vivo
  publication-title: J?Photochem Photobiol A: Chem
  doi: 10.1016/S1010-6030(96)04371-7
  contributor:
    fullname: Jori
– volume: 14
  start-page: 71
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib3
  article-title: Near-infrared fluorescence: application to in?vivo molecular imaging
  publication-title: Curr Opin Chem Biol
  doi: 10.1016/j.cbpa.2009.09.029
  contributor:
    fullname: Hilderbrand
– volume: 61
  start-page: 131
  year: 2009
  ident: 10.1016/j.dyepig.2012.05.012_bib22
  article-title: Design considerations towards simultaneously radiolabeled and fluorescent imaging probes incorporating metallic species
  publication-title: Adv Inorg Chem
  doi: 10.1016/S0898-8838(09)00203-7
  contributor:
    fullname: Pascu
– volume: 59
  start-page: 969
  year: 2008
  ident: 10.1016/j.dyepig.2012.05.012_bib28
  article-title: Microwave-assisted synthesis of unsymmetrical tetrapyrrolic compounds
  publication-title: Revista De Chim
  contributor:
    fullname: Socoteanu
– volume: 109
  start-page: 392
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib11
  article-title: Susceptibility of Candida albicans to photodynamic therapy in a murine model of oral candidosis
  publication-title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  doi: 10.1016/j.tripleo.2009.10.006
  contributor:
    fullname: de Oliveira Mima
– volume: 63
  start-page: 195
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib10
  article-title: Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practice Part II. Understanding parameters for acne treatment with photodynamic therapy
  publication-title: J?Am Acad Dermatol
  doi: 10.1016/j.jaad.2009.09.057
  contributor:
    fullname: Sakamoto
– volume: 57
  start-page: 90
  year: 2000
  ident: 10.1016/j.dyepig.2012.05.012_bib20
  article-title: Measurement of the penetration depths of red and near infrared light in human ?ex?vivo? tissues
  publication-title: J?Photochem Photobiol B
  doi: 10.1016/S1011-1344(00)00082-8
  contributor:
    fullname: Stolik
– volume: 7
  start-page: 61
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib42
  article-title: Oncologic photodynamic therapy photosensitizers: a clinical review
  publication-title: Photodiagnosis Photodyn Ther
  doi: 10.1016/j.pdpdt.2010.02.001
  contributor:
    fullname: Allison
– volume: 3
  start-page: 772
  year: 2004
  ident: 10.1016/j.dyepig.2012.05.012_bib2
  article-title: Ypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder
  publication-title: Photochem Photobiol Sci
  doi: 10.1039/b315586b
  contributor:
    fullname: Kamuhabwa
– volume: 38
  start-page: 445
  year: 2006
  ident: 10.1016/j.dyepig.2012.05.012_bib43
  article-title: Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy
  publication-title: Lasers Surg Med
  doi: 10.1002/lsm.20352
  contributor:
    fullname: Pandey
– volume: 26
  start-page: 1501
  year: 2005
  ident: 10.1016/j.dyepig.2012.05.012_bib8
  article-title: Photodynamic diagnosis of a human nasopharyngeal carcinoma xenograft model using the novel chlorin e6 photosensitizer fotolon
  publication-title: Int J Oncol
  contributor:
    fullname: Ramaswamy
– volume: 2
  start-page: 926
  year: 2003
  ident: 10.1016/j.dyepig.2012.05.012_bib24
  article-title: Photodynamic activity of monocationic and no-charged methoxyphenylporphyrin derivatives in homogeneous and biological media
  publication-title: Photochem Photobiol Sci
  doi: 10.1039/B212890J
  contributor:
    fullname: Milanesio
– volume: 82
  start-page: 509
  year: 2008
  ident: 10.1016/j.dyepig.2012.05.012_bib16
  article-title: Synthesis and characterisation of some new unsymmetrically-substituted mesoporphyrinic mono-hydroxyphenyl complexes of Cu(II)
  publication-title: Polish J Chem
  contributor:
    fullname: Boscencu
– volume: 1065
  start-page: 42
  year: 1991
  ident: 10.1016/j.dyepig.2012.05.012_bib23
  article-title: Liposomes as models to study the distribution of porphyrins in cell membranes
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0005-2736(91)90008-V
  contributor:
    fullname: Ricchelli
– start-page: 1
  year: 1978
  ident: 10.1016/j.dyepig.2012.05.012_bib36
  article-title: Optical spectra and electronic structure of porphyrins and related rings
  doi: 10.1016/B978-0-12-220103-5.50008-8
  contributor:
    fullname: Gouterman
– volume: 49
  start-page: 770
  year: 2010
  ident: 10.1016/j.dyepig.2012.05.012_bib12
  article-title: Singlet oxygen in Escherichia coli: new insights for antimicrobial photodynamic therapy
  publication-title: Free Radic Biol Med
  doi: 10.1016/j.freeradbiomed.2010.05.027
  contributor:
    fullname: Rag?s
– volume: 37
  start-page: 306
  year: 2005
  ident: 10.1016/j.dyepig.2012.05.012_bib25
  article-title: Meso-substituted tetra-cationic porphyrins photosensitize the death of human fibrosarcoma cells via lysosomal targeting
  publication-title: Int J Biochem Cell Biol
  doi: 10.1016/j.biocel.2004.06.013
  contributor:
    fullname: Riccheli
– volume: 64
  start-page: 469
  year: 1996
  ident: 10.1016/j.dyepig.2012.05.012_bib21
  article-title: Structure and biodistribution relationships of photodynamic sensitizers
  publication-title: Photochem Photobiol
  doi: 10.1111/j.1751-1097.1996.tb03093.x
  contributor:
    fullname: Boyle
– volume: 64
  start-page: 313
  year: 1983
  ident: 10.1016/j.dyepig.2012.05.012_bib29
  article-title: An enzyme-release assay for natural cytotoxicity
  publication-title: J?Immunol Meth
  doi: 10.1016/0022-1759(83)90438-6
  contributor:
    fullname: Korzeniewski
– volume: 5
  start-page: 497
  year: 2004
  ident: 10.1016/j.dyepig.2012.05.012_bib41
  article-title: The present and future role of photodynamic therapy in cancer treatment
  publication-title: Lancet Oncol
  doi: 10.1016/S1470-2045(04)01529-3
  contributor:
    fullname: Brown
– volume: 15
  start-page: 93
  year: 1988
  ident: 10.1016/j.dyepig.2012.05.012_bib38
  article-title: NATO ASI Ser
  publication-title: Ser H
  contributor:
    fullname: Rechmond
– volume: 344
  start-page: 78
  year: 2007
  ident: 10.1016/j.dyepig.2012.05.012_bib5
  article-title: Tetrapyrrole-photosensitizers vectorization and plasma LDL: a physic-chemical approach
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2007.06.019
  contributor:
    fullname: Bonneau
– volume: 245
  start-page: 127
  year: 2007
  ident: 10.1016/j.dyepig.2012.05.012_bib6
  article-title: Chlorin e6-polyvinylpyrrolidone as a fluorescent marker for fluorescence diagnosis of human bladder cancer implanted on the chick chorioallantoic membrane model
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2005.12.041
  contributor:
    fullname: Chin
– volume: 218
  start-page: 133
  year: 2005
  ident: 10.1016/j.dyepig.2012.05.012_bib7
  article-title: Porphyrin related photosensitizers for cancer imaging and therapeutic applications
  publication-title: J?Microsc
  doi: 10.1111/j.1365-2818.2005.01471.x
  contributor:
    fullname: Berg
– volume: 73
  start-page: 713
  year: 2008
  ident: 10.1016/j.dyepig.2012.05.012_bib17
  article-title: Studies on Zn(II) Monohydroxyphenyl substituted mesoporphyrins synthesis and characterisation
  publication-title: J?Serbian Chem Soc
  doi: 10.2298/JSC0807713B
  contributor:
    fullname: Boscencu
– volume: 29
  start-page: 109
  year: 1995
  ident: 10.1016/j.dyepig.2012.05.012_bib26
  article-title: Photophysical properties of porphyrins in biological membranes
  publication-title: J?Photochem Photobiol B: Biol
  doi: 10.1016/1011-1344(95)07155-U
  contributor:
    fullname: Riccheli
– volume: 35
  start-page: 149
  year: 1961
  ident: 10.1016/j.dyepig.2012.05.012_bib35
  article-title: ESR studies on the bonding in copper complexes
  publication-title: J?Chem Phys
  contributor:
    fullname: Kivelson
– start-page: 358
  year: 1978
  ident: 10.1016/j.dyepig.2012.05.012_bib33
  article-title: Electron spin resonance and electronic structure of metalloporphyrins
  contributor:
    fullname: Lin
– volume: 25
  start-page: 623
  year: 2004
  ident: 10.1016/j.dyepig.2012.05.012_bib13
  article-title: Evaluation of hypocrellin B in a human bladder tumor model in experimental photodynamic therapy: biodistribution, light dose and drug-light interval effects
  publication-title: Int J Oncol
  contributor:
    fullname: Chin
– volume: 84
  start-page: 213
  year: 2006
  ident: 10.1016/j.dyepig.2012.05.012_bib27
  article-title: Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines
  publication-title: J?Photochem Photobiol B Biol
  doi: 10.1016/j.jphotobiol.2006.03.006
  contributor:
    fullname: Zhenyu
– volume: 60
  start-page: 1006
  year: 2009
  ident: 10.1016/j.dyepig.2012.05.012_bib14
  article-title: Synthesis, spectral and biological evaluation of some mesoporphyrinic complexes of Zn(II)
  publication-title: Revista De Chim
  contributor:
    fullname: Boscencu
– volume: 58
  start-page: 498
  year: 2007
  ident: 10.1016/j.dyepig.2012.05.012_bib18
  article-title: Synthesis and spectral characterisation of some unsymmetrically substituted mesoporphyrinic compounds
  publication-title: Revista De Chim
  contributor:
    fullname: Boscencu
– volume: 53
  start-page: 88
  year: 1974
  ident: 10.1016/j.dyepig.2012.05.012_bib39
  article-title: Porphyrin free base phosphorescence
  publication-title: J?Mol Spectrosc
  doi: 10.1016/0022-2852(74)90263-X
  contributor:
    fullname: Gouterman
– volume: 1
  start-page: 611
  year: 1991
  ident: 10.1016/j.dyepig.2012.05.012_bib30
  publication-title: Bioorg Med Chem Lett
  doi: 10.1016/S0960-894X(01)81162-8
  contributor:
    fullname: Barltrop
– start-page: 275
  year: 2001
  ident: 10.1016/j.dyepig.2012.05.012_bib32
  article-title: Photonic and electronic spectroscopies for the characterization of organic surfaces and organic molecules adsorbed on surfaces
  doi: 10.1016/B978-012513910-6/50026-8
  contributor:
    fullname: Botelho do Rego
– volume: 47
  start-page: 3897
  year: 2004
  ident: 10.1016/j.dyepig.2012.05.012_bib1
  article-title: Current clinical and Preclinical photosensitizers for use in photodynamic therapy
  publication-title: J?Med Chem
  doi: 10.1021/jm040074b
  contributor:
    fullname: Detty
SSID ssj0008321
Score 2.0496845
Snippet A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were...
A series of some A3B type mesoporphyrinic compounds were synthesized with superior yields using the microwave irradiation. The prepared compounds were...
SourceID proquest
crossref
elsevier
SourceType Aggregation Database
Publisher
StartPage 296
SubjectTerms Activation
Cytotoxicity
Derivatives
Fluorescence
Maxima
Molecular absorption
Molecular structure
Singlet oxygen
Solvents
Unsymmetrical mesoporphyrins
Zinc
Title Synthesis, photophysical and cytotoxicity evaluation of A3B type mesoporphyrinic compounds
URI https://dx.doi.org/10.1016/j.dyepig.2012.05.012
https://search.proquest.com/docview/1671412279
Volume 95
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ba9swFD4kKaXdw9iyjnWXoEEf68W2LF8e07CQNdCHtqGhL8KypM2D2aFOYHnZb985vvQyGIM9CQuOMUfyd46kT98BOLFJrDKriefncyfIUpc2moSjQ2tt6Aeha2q1z4twvgzOV2LVg2l3F4ZolS32N5heo3XbM269OV7n-ZhoSVRiBSNUzVYM-7CH4YjOavcmXxbzi3tApmI8DZORO2TQ3aCraV56Z9b5V-J4-Y2Ep_-3CPUHVtcBaPYCnreZI5s0H_cSeqYYwsG0K9g2hGePtAWHsF9zO7PqFdxe7QpM86q8OmXrbyUpCTRjw9JCs2y3wa6feYbpOHvQ_malZRN-xmiLlv0wVYl5OtrReU_GiIdO5ZiqI1jOPl9P505bUsHJcCmXOEp5SiVRlsYY5rWOuPGVl8S6_nn9yKQxLq4DYa0y3LqJ8XhsYmV9L0hVKjCXeQ2DoizMG2DCumFsIky_uA2M9lNhERysEdxq4wpxDE7nRrlulDNkRyn7Lhu3S3K7dIXE5hiiztfyyQyQCO7_sPzYDY1El9OJR1qYcltJL4xwZpBI4tv_fvs7OKSn5v7hexhs7rbmAyYiGzWC_qdf3qidbtQuLm8WvwG0veB5
link.rule.ids 314,780,784,4502,24116,27924,27925,45585,45679
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ZS8QwEB48EPVBdFVczwg-WrdXejzqoqzniwriS2iaRCvYLnYF98Xf7kwPPEAEnwppU8pMOvMl-fINwJ6JI5kaRTw_17P8NLFpoYlbKjDGBK4f2LpS-7wKBrf-2R2_m4B-exaGaJVN7K9jehWtm5ZeY83eMMt6REuiEiuYoSq2YjAJ0z5H9IuD-uD9k-dBpXhqHqNn0ePt-bmK5KXGepg9EMPLrQU83d_y049IXaWfk0VYaHAjO6w_bQkmdN6B2X5brq0D81-UBTswUzE703IZ7q_HOYK8Miv32fCxIB2B2jMsyRVLxyNsestSBOPsU_mbFYYdekeMFmjZsy4LROnYj3Z7UkYsdCrGVK7A7cnxTX9gNQUVrBQncrElpSNlHKZJhEleqdDTrnTiSFW_rhvqJMKptc-NkdozdqwdL9KRNK7jJzLhiGRWYSovcr0GjBs7iHSI4MszvlZuwg2GBqO5Z5S2Oe-C1ZpRDGvdDNESyp5EbXZBZhc2F3jpQtjaWnzzv8DQ_kfP3dY1Ak1O-x1JrovXUjhBiOOCJBLX__32HZgd3FxeiIvTq_MNmKM79UnETZgavbzqLYQkI7ldDbkPvjPfrw
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Synthesis%2C+photophysical+and+cytotoxicity+evaluation+of+A3B+type+mesoporphyrinic+compounds&rft.jtitle=Dyes+and+pigments&rft.au=Vieira+Ferreira%2C+Luis+F&rft.au=Ferreira%2C+Diana+P&rft.au=Oliveira%2C+Anabela+S&rft.au=Boscencu%2C+Rica&rft.date=2012-11-01&rft.issn=0143-7208&rft.volume=95&rft.issue=2&rft.spage=296&rft.epage=303&rft_id=info:doi/10.1016%2Fj.dyepig.2012.05.012&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0143-7208&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0143-7208&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0143-7208&client=summon