Oxorhenium(V) complexes with pyridinedicarboxylic ligands: Synthesis, density functional theory calculations, and drug combination study

• Published in: Applied organometallic chemistry Vol. 38; no. 9
• Main Authors: Petrović, Tamara, Gligorijević, Nevenka, Medaković, Vesna, Veljković, Dušan, Aranđelović, Sandra, Grgurić‐Šipka, Sanja, Poljarević, Jelena
• Format: Journal Article
• Language: English
• Published: Chichester Wiley Subscription Services, Inc 01.09.2024
• Subjects: antiproliferative activity; Antiproliferatives; Chemical activity; Chemical compounds; Chemical synthesis; Density functional theory; DFT calculations; drug combination study; Efflux; Glycoproteins; oxorhenium(V) complexes; Rhenium; verapamil

Three oxorhenium(V) complexes [ReOLCl2(PPh3)] (C1–C3) were synthesized in the reaction of 2,3‐pyridinedicarboxylic acid (HL1), 2,5‐pyridinedicarboxylic acid (HL2), and 2,6‐pyridinedicarboxylic acid (HL3) with [ReOCl3(PPh3)2]. Chemical structures of synthesized compounds were confirmed using standard...