Retention, stability, iron bioavailability and sensory evaluation of extruded rice fortified with iron, folic acid and vitamin B 12
Fortification of rice with micronutrients using extrusion technology is considered a sustainable strategy to prevent nutritional deficiencies in general population. The objective of the present study is to assess the retention, stability and iron bioavailability from indigenously developed triple fo...
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Published in | Maternal and child nutrition Vol. 16; no. S3; p. e12932 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
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01.12.2020
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Abstract | Fortification of rice with micronutrients using extrusion technology is considered a sustainable strategy to prevent nutritional deficiencies in general population. The objective of the present study is to assess the retention, stability and iron bioavailability from indigenously developed triple fortified rice (iron, folic acid and vitamin B
12
) during rinsing and different cooking methods. Further, we also assessed the acceptability of fortified rice in adult human volunteers. The retention of iron during rinsing with excess water was ≥90%, whereas folic acid and vitamin B
12
levels were reduced by ~25% during rinsing. Watertight cooking of rice (in electric cooker or on flame) had no additional effect on the nutrient levels as compared with rinsed rice, implying their stability during cooking. However, cooking with excess water followed by decanting led to loss of 45% iron and ≥70% folic acid and vitamin B
12
. The dialyzable iron and ferritin synthesis in Caco‐2 cells was significantly (
P
< .01) higher from fortified rice compared with unfortified rice. In addition, inclusion of ascorbic acid significantly (
P
< .01) increased the iron bioavailability from the fortified rice. Triangle tests in adult human subjects revealed that there are no significant sensory differences among fortified and unfortified rice. Further, fortified rice consumption appears to bridge the gaps in dietary iron intake deficits in children and women of reproductive age. These results suggest that the iron‐, folic acid‐ and vitamin B
12
‐fortified rice has higher retention and stability of fortified nutrients and is acceptable for consumption in adult human volunteers. |
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AbstractList | Fortification of rice with micronutrients using extrusion technology is considered a sustainable strategy to prevent nutritional deficiencies in general population. The objective of the present study is to assess the retention, stability and iron bioavailability from indigenously developed triple fortified rice (iron, folic acid and vitamin B
12
) during rinsing and different cooking methods. Further, we also assessed the acceptability of fortified rice in adult human volunteers. The retention of iron during rinsing with excess water was ≥90%, whereas folic acid and vitamin B
12
levels were reduced by ~25% during rinsing. Watertight cooking of rice (in electric cooker or on flame) had no additional effect on the nutrient levels as compared with rinsed rice, implying their stability during cooking. However, cooking with excess water followed by decanting led to loss of 45% iron and ≥70% folic acid and vitamin B
12
. The dialyzable iron and ferritin synthesis in Caco‐2 cells was significantly (
P
< .01) higher from fortified rice compared with unfortified rice. In addition, inclusion of ascorbic acid significantly (
P
< .01) increased the iron bioavailability from the fortified rice. Triangle tests in adult human subjects revealed that there are no significant sensory differences among fortified and unfortified rice. Further, fortified rice consumption appears to bridge the gaps in dietary iron intake deficits in children and women of reproductive age. These results suggest that the iron‐, folic acid‐ and vitamin B
12
‐fortified rice has higher retention and stability of fortified nutrients and is acceptable for consumption in adult human volunteers. Fortification of rice with micronutrients using extrusion technology is considered a sustainable strategy to prevent nutritional deficiencies in general population. The objective of the present study is to assess the retention, stability and iron bioavailability from indigenously developed triple fortified rice (iron, folic acid and vitamin B ) during rinsing and different cooking methods. Further, we also assessed the acceptability of fortified rice in adult human volunteers. The retention of iron during rinsing with excess water was ≥90%, whereas folic acid and vitamin B levels were reduced by ~25% during rinsing. Watertight cooking of rice (in electric cooker or on flame) had no additional effect on the nutrient levels as compared with rinsed rice, implying their stability during cooking. However, cooking with excess water followed by decanting led to loss of 45% iron and ≥70% folic acid and vitamin B . The dialyzable iron and ferritin synthesis in Caco-2 cells was significantly (P < .01) higher from fortified rice compared with unfortified rice. In addition, inclusion of ascorbic acid significantly (P < .01) increased the iron bioavailability from the fortified rice. Triangle tests in adult human subjects revealed that there are no significant sensory differences among fortified and unfortified rice. Further, fortified rice consumption appears to bridge the gaps in dietary iron intake deficits in children and women of reproductive age. These results suggest that the iron-, folic acid- and vitamin B -fortified rice has higher retention and stability of fortified nutrients and is acceptable for consumption in adult human volunteers. |
Author | Thingnganing, Longvah Jyrwa, Yvette Wilda Boddula, Swetha Boiroju, Naveen Kumar Palika, Ravindranadh Pullakhandam, Raghu Madhari, Radhika |
Author_xml | – sequence: 1 givenname: Yvette Wilda surname: Jyrwa fullname: Jyrwa, Yvette Wilda organization: Micronutrient Research Group, Biochemistry Division National Institute of Nutrition Hyderabad India – sequence: 2 givenname: Ravindranadh surname: Palika fullname: Palika, Ravindranadh organization: Micronutrient Research Group, Biochemistry Division National Institute of Nutrition Hyderabad India – sequence: 3 givenname: Swetha surname: Boddula fullname: Boddula, Swetha organization: Clinical Division National Institute of Nutrition Hyderabad India – sequence: 4 givenname: Naveen Kumar surname: Boiroju fullname: Boiroju, Naveen Kumar organization: Biostatistics Division National Institute of Nutrition Hyderabad India – sequence: 5 givenname: Radhika orcidid: 0000-0003-2009-1475 surname: Madhari fullname: Madhari, Radhika organization: Clinical Division National Institute of Nutrition Hyderabad India – sequence: 6 givenname: Raghu orcidid: 0000-0002-3758-667X surname: Pullakhandam fullname: Pullakhandam, Raghu organization: Micronutrient Research Group, Biochemistry Division National Institute of Nutrition Hyderabad India – sequence: 7 givenname: Longvah orcidid: 0000-0002-5528-8676 surname: Thingnganing fullname: Thingnganing, Longvah organization: Food Chemistry Division National Institute of Nutrition, Indian Council of Medical Research Hyderabad India |
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Keywords | iron vitamin B12 folic acid bioavailability fortified rice sensory properties |
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References | e_1_2_9_30_1 e_1_2_9_31_1 e_1_2_9_11_1 Nair K. M. (e_1_2_9_24_1) 2009; 130 e_1_2_9_34_1 e_1_2_9_10_1 Shalini T. (e_1_2_9_33_1) 2018; 58 e_1_2_9_32_1 e_1_2_9_12_1 WHO (e_1_2_9_39_1) 2006 e_1_2_9_15_1 e_1_2_9_38_1 e_1_2_9_14_1 e_1_2_9_17_1 Laxmaiah A. (e_1_2_9_16_1) 2012; 15 Ghosh S. (e_1_2_9_8_1) 2019; 56 e_1_2_9_19_1 e_1_2_9_18_1 e_1_2_9_20_1 e_1_2_9_40_1 e_1_2_9_22_1 Sreenivasulu K. (e_1_2_9_37_1) 2008; 56 e_1_2_9_21_1 Silveira C. M. M. (e_1_2_9_35_1) 2016; 28 e_1_2_9_23_1 e_1_2_9_7_1 e_1_2_9_6_1 e_1_2_9_5_1 e_1_2_9_4_1 e_1_2_9_3_1 e_1_2_9_2_1 Sivakumar B. (e_1_2_9_36_1) 2006; 22 Hurrell R. F. (e_1_2_9_13_1) 2002; 132 e_1_2_9_9_1 e_1_2_9_26_1 e_1_2_9_25_1 e_1_2_9_28_1 e_1_2_9_27_1 e_1_2_9_29_1 |
References_xml | – ident: e_1_2_9_25_1 – ident: e_1_2_9_22_1 doi: 10.1177/156482651203300410 – ident: e_1_2_9_17_1 doi: 10.1016/j.bbacli.2017.09.001 – volume: 22 start-page: S15 issue: 1 year: 2006 ident: e_1_2_9_36_1 article-title: Effect of micronutrient supplement on health and nutritional status of schoolchildren: biochemical status publication-title: Nutrition doi: 10.1016/j.nut.2005.07.012 – ident: e_1_2_9_7_1 – volume: 58 start-page: 1 year: 2018 ident: e_1_2_9_33_1 article-title: Micronutrient intakes and status assessed by probability approach among the urban adult population of Hyderabad city in South India publication-title: European Journal of Nutrition – ident: e_1_2_9_9_1 doi: 10.1093/jn/nxy283 – ident: e_1_2_9_20_1 doi: 10.1111/j.1365-2621.2005.tb09987.x – ident: e_1_2_9_40_1 doi: 10.1111/nyas.12497 – volume: 56 start-page: 551 issue: 7 year: 2019 ident: e_1_2_9_8_1 article-title: Daily Iron Requirements in Healthy Indian Children and Adolescents publication-title: Indian Pediatrics doi: 10.1007/s13312-019-1552-0 – ident: e_1_2_9_19_1 doi: 10.1111/j.1365-2621.2012.03035.x – volume: 132 start-page: 806S issue: 4 year: 2002 ident: e_1_2_9_13_1 article-title: Fortification: Overcoming technical and practical barriers publication-title: The Journal of Nutrition doi: 10.1093/jn/132.4.806S – ident: e_1_2_9_15_1 doi: 10.1016/j.lwt.2010.06.001 – ident: e_1_2_9_4_1 doi: 10.1016/j.foodchem.2008.07.089 – ident: e_1_2_9_18_1 doi: 10.1201/9781003040729 – ident: e_1_2_9_32_1 – ident: e_1_2_9_34_1 doi: 10.1080/09637486.2016.1226273 – ident: e_1_2_9_12_1 doi: 10.1177/156482650802900208 – ident: e_1_2_9_14_1 doi: 10.1111/nyas.12506 – volume: 130 start-page: 634 issue: 5 year: 2009 ident: e_1_2_9_24_1 article-title: Iron content, bioavailability & factors affecting iron status of Indians publication-title: The Indian Journal of Medical Research – ident: e_1_2_9_5_1 doi: 10.1093/jn/130.5.1329 – ident: e_1_2_9_27_1 – ident: e_1_2_9_10_1 doi: 10.1093/jn/128.9.1555 – ident: e_1_2_9_6_1 doi: 10.3945/jn.109.112623 – ident: e_1_2_9_31_1 doi: 10.3945/ajcn.110.007179 – ident: e_1_2_9_23_1 doi: 10.1017/S1368980015002050 – ident: e_1_2_9_38_1 doi: 10.1111/nyas.12418 – ident: e_1_2_9_3_1 doi: 10.1024/0300-9831.78.2.74 – ident: e_1_2_9_28_1 doi: 10.1021/jf403973j – volume: 56 start-page: 10967 issue: 22 year: 2008 ident: e_1_2_9_37_1 article-title: Effect of dietary ligands and food matrices on zinc uptake in Caco‐2 cells: implications in assessing zinc bioavailability publication-title: Journal of Agricultural and Food Chemistry doi: 10.1021/jf802060q – volume: 15 start-page: 568 issue: 4 year: 2012 ident: e_1_2_9_16_1 article-title: Prevalence of ocular signs and subclinical vitamin A deficiency and its determinants among rural pre‐school children in India publication-title: Public Health Nutrition doi: 10.1017/S136898001100214X – volume: 28 start-page: 455 issue: 4 year: 2016 ident: e_1_2_9_35_1 article-title: Methods for analysis of thiamin and folic acid by HPLC—DAD in fortified rice pure and mixed to milled rice before and after different cooking techniques publication-title: Acta Chromatographica doi: 10.1556/1326.2016.28.4.3 – ident: e_1_2_9_2_1 doi: 10.1093/jn/136.4.1055 – ident: e_1_2_9_26_1 – ident: e_1_2_9_29_1 doi: 10.1111/j.1365-2621.1982.tb11073.x – ident: e_1_2_9_21_1 doi: 10.1093/ajcn/84.4.822 – volume-title: World Health Organization. Guidelines on food fortification with micronutrients year: 2006 ident: e_1_2_9_39_1 – ident: e_1_2_9_11_1 doi: 10.1016/j.chroma.2005.09.059 – ident: e_1_2_9_30_1 doi: 10.1111/j.1750-3841.2010.01993.x |
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Title | Retention, stability, iron bioavailability and sensory evaluation of extruded rice fortified with iron, folic acid and vitamin B 12 |
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