Inclusion of South African adolescents in HIV vaccine trials

South Africa has more people living with HIV than any other nation. The HIV epidemic in South Africa is being driven by new infections among adolescents. Inclusion of adolescents in HIV vaccine trials is essential for successful vaccine development, however, recruitment and retention of at-risk Sout...

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Bibliographic Details
Published inJournal of AIDS and HIV research Vol. 4; no. 2; pp. 30 - 35
Main Author Adler, David H
Format Journal Article
LanguageEnglish
Published Kenya 01.02.2012
Subjects
South Africa
HIV vaccine trial
recruitment
retention
Adolescent
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Summary:South Africa has more people living with HIV than any other nation. The HIV epidemic in South Africa is being driven by new infections among adolescents. Inclusion of adolescents in HIV vaccine trials is essential for successful vaccine development, however, recruitment and retention of at-risk South African adolescents into these trials poses a number of legal, ethical and operational challenges. This article discusses the South African ethico-legal context in which future adolescent HIV vaccine trials would be conducted followed by a review of available data regarding strategies for recruitment into these trials and retention of trial participants.
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ISSN:2141-2359
2141-2359
DOI:10.5897/JAHR11.065