Effects of different compounding of formulae on content of gardenoside in Yin Chen Hao decoction

In order to observe the effects of the ground and intact Zhi Zi (Fructus Gardeniae) and different combinations of the ingredients and refined single Chinese drug granules in Yin Chen Hao Decoction compound prescription on the contents of gardenoside (an effective component of the prescription), the...

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Bibliographic Details
Published inJournal of traditional Chinese medicine Vol. 22; no. 1; p. 55
Main Authors Liang, Guangyi, Cao, Peixue, Chai, Li, Xian, Furong, Li, Xia
Format Journal Article
LanguageEnglish
Published China 01.03.2002
Subjects
Chromatography, High Pressure Liquid - methods
Drug Compounding
Drugs, Chinese Herbal - chemistry
Iridoids
Pyrans - analysis
Technology, Pharmaceutical
Online AccessGet more information
ISSN0255-2922

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Summary:In order to observe the effects of the ground and intact Zhi Zi (Fructus Gardeniae) and different combinations of the ingredients and refined single Chinese drug granules in Yin Chen Hao Decoction compound prescription on the contents of gardenoside (an effective component of the prescription), the contents of gardenoside were determined with reversed phase high performance liquid chromatography (HPLC), with acetonitrile-water (15:85) as mobile phase, at wave length 238 nm. The results indicated that the gardenoside-decocted-out rates in the decoctions prepared by different combinations of the ingredients with the ground Zhi Zi (Fructus Gardeniae) all were higher significantly than those in the decoction with intact Zhi Zi (Fructus Gardeniae), and generally, different combinations of the ingredients in the decoction had only little effect on the gardenoside-decocted-out rate.
ISSN:0255-2922