Utilization of the QuPath open-source software platform for analysis of mammalian spermatogenesis

• Published in: Biology of reproduction Vol. 112; no. 3; pp. 583 - 599
• Main Authors: Niedenberger, Bryan A, Belcher, Heather A, Gilbert, Emma A, Thomas, Matthew A, Geyer, Christopher B
• Format: Journal Article
• Language: English
• Published: United States 16.03.2025
• Subjects: Animals; Male; Mice; Software; Spermatogenesis - physiology; Testis - cytology; Testis - physiology; spermatocyte; Sertoli cell; spermatogonia; testis; software; spermatid

The adult mammalian testis is filled with seminiferous tubules, which contain somatic Sertoli cells along with germ cells undergoing all phases of spermatogenesis. During spermatogenesis in postnatal mice, male germ cells undergo at least 17 different nomenclature changes as they proceed through mit...