Reproducibility of R 2 and quantitative susceptibility mapping (QSM) reconstruction methods in the basal ganglia of healthy subjects

• Published in: NMR in biomedicine Vol. 30; no. 4
• Main Authors: Santin, M. D., Didier, M., Valabrègue, R., Yahia Cherif, L., García‐Lorenzo, D., Loureiro de Sousa, P., Bardinet, E., Lehéricy, S.
• Format: Journal Article
• Language: English
• Published: England 01.04.2017
• Subjects: Adult; Algorithms; Basal Ganglia - diagnostic imaging; Basal Ganglia - metabolism; Biomarkers - metabolism; Female; Humans; Image Interpretation, Computer-Assisted - methods; Iron - metabolism; Magnetic Resonance Imaging - methods; Male; Molecular Imaging - methods; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Young Adult; R2; neurological diseases; basal ganglia; quantitative susceptibility mapping (QSM); relaxometry; reproducibility; brain

The basal ganglia are key structures for motor, cognitive and behavioral functions. They undergo several changes with aging and disease, such as Parkinson's or Huntington's disease, for example. Iron accumulation in basal ganglia is often related to these diseases, which is conventionally...