Reappraisal of statin primary prevention trials: implications for identification of the statin-eligible primary prevention patient

• Published in: European journal of preventive cardiology
• Main Authors: Mancini, G B John, Ryomoto, Arnold, Yeoh, Eunice, Iatan, Iulia, Brunham, Liam R, Hegele, Robert A
• Format: Journal Article
• Language: English
• Published: England 25.02.2025
• Subjects: primary prevention; randomized clinical trials; Systematic Coronary Risk Estimate; Pooled Cohort Equation; statin; Framingham Risk Score

Identification of patients eligible for primary prevention statin therapy is complex, often relying upon risk algorithms that diverge internationally. Our goal was to develop a simpler global definition of statin-eligible primary prevention patients. Randomized clinical trials (RCTs) cited in North...