Expression of intercellular adhesion molecule in lung tissues of experimental acute lung injury and the affect of Rhubarb on it

• Published in: Chinese medical sciences journal Vol. 15; no. 2; p. 93
• Main Authors: Chunsheng, L, Peichun, G, Xinhua, H
• Format: Journal Article
• Language: English
• Published: China 01.06.2000
• Subjects: Animals; Anti-Inflammatory Agents - pharmacology; Dexamethasone - pharmacology; Drugs, Chinese Herbal - isolation & purification; Drugs, Chinese Herbal - pharmacology; Intercellular Adhesion Molecule-1 - biosynthesis; Intercellular Adhesion Molecule-1 - genetics; Lipopolysaccharides; Male; Plants, Medicinal - chemistry; Rats; Rats, Wistar; Respiratory Distress Syndrome, Adult - chemically induced; Respiratory Distress Syndrome, Adult - metabolism; Respiratory Distress Syndrome, Adult - pathology; Rheum - chemistry; RNA, Messenger - genetics

To approach the relation and the possible mechanism between the expression of intercellular adhesion molecule (ICAM-1) mRNA and acute lung injury (ALI) and the mechanisms of rhubarb in the prevention and treatment of the lung injury. Lipopolysaccharide (LPS) was injected into the sublingual vein of...