A modeling and control framework for extraction processes

• Published in: Chemical engineering science Vol. 298; p. 120384
• Main Authors: Boehm, Joscha, Moser, Daniel, Neugebauer, Peter, Rehrl, Jakob, Poechlauer, Peter, Kirschneck, Dirk, Horn, Martin, Steinberger, Martin, Sacher, Stephan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 05.10.2024
• Subjects: Advanced process control; Continuous manufacturing; Control concept; Liquid–liquid-extraction; Model-based control; Process modeling; Continuous manufacturing; Process modeling; Control concept; Liquid–liquid-extraction; Advanced process control; Model-based control

•Efficient active process control of a pharmaceutical purification step.•Universally applicable development procedure for process models.•Process modeling approach capable for early development stages.•Evaluation of control concepts with different real-time measurements.•Process route selection base...