Sex and APOE Genotype Influence Respiratory Function Under Hypoxic and Hypoxic-Hypercapnic Conditions

• Published in: Journal of neurophysiology Vol. 132; no. 1; pp. 23 - 33
• Main Authors: Taylor, Chase E, Mendenhall, Laura E, Sunshine, Michael D, Wilson, Jessica N, Calulot, Chris M, Sun, Ramon C, Johnson, Lance A, Alilain, Warren J
• Format: Journal Article
• Language: English
• Published: United States 01.07.2024
• Subjects: Hypercapnia; Hypoxia; APOE; Breathing; Sex

The apolipoprotein gene has been studied due to its influence on Alzheimer's disease (AD) development and work in an mouse model recently demonstrated impaired respiratory motor plasticity following spinal cord injury (SCI). Individuals with AD often co-present with obstructive sleep apnea (OSA...