Identifying the Zika Virus Target Cell in Malignant Glioma

• Published in: Neuro-oncology (Charlottesville, Va.) Vol. 21; no. Supplement_4; p. iv2
• Main Authors: Girdler, Gemma, Gracia, Tannia, Fountain, Daniel, Fajardo Jr, Ted, Finlay, Jack, Hallou, Clément, Pollard, Steve, Sweeney, Trevor, Gergely, Fanni, Rowitch, David, Bulstrode, Harry
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 12.10.2019
• Subjects: Abstracts

Abstract The Zika Virus epidemic of 2015–2016 was associated with striking failure of forebrain development in infants born to infected mothers, resulting in microcephaly. Studies from numerous labs subsequently confirmed a selective effect of the virus on neural stem cell survival, self-renewal and...