Interruption of the Ionic Lock in the Bradykinin B 2 Receptor Results in Constitutive Internalization and Turns Several Antagonists into Strong Agonists

Saved in:
Bibliographic Details
Published inThe Journal of pharmacology and experimental therapeutics Vol. 344; no. 1; pp. 85 - 95
Main Authors Leschner, Jasmin, Wennerberg, Goeran, Feierler, Jens, Bermudez, Marcel, Welte, Benjamin, Kalatskaya, Irina, Wolber, Gerhard, Faussner, Alexander
Format Journal Article
LanguageEnglish
Published 01.01.2013
Online AccessGet full text

Cover

Author Bermudez, Marcel
Faussner, Alexander
Wolber, Gerhard
Wennerberg, Goeran
Welte, Benjamin
Leschner, Jasmin
Kalatskaya, Irina
Feierler, Jens
Author_xml – sequence: 1
  givenname: Jasmin
  surname: Leschner
  fullname: Leschner, Jasmin
– sequence: 2
  givenname: Goeran
  surname: Wennerberg
  fullname: Wennerberg, Goeran
– sequence: 3
  givenname: Jens
  surname: Feierler
  fullname: Feierler, Jens
– sequence: 4
  givenname: Marcel
  surname: Bermudez
  fullname: Bermudez, Marcel
– sequence: 5
  givenname: Benjamin
  surname: Welte
  fullname: Welte, Benjamin
– sequence: 6
  givenname: Irina
  surname: Kalatskaya
  fullname: Kalatskaya, Irina
– sequence: 7
  givenname: Gerhard
  surname: Wolber
  fullname: Wolber, Gerhard
– sequence: 8
  givenname: Alexander
  surname: Faussner
  fullname: Faussner, Alexander
BookMark eNotkM1uwjAQhK2KSgXac69-gYA3dpL6CKg_SJEqFe6RsR1qSO3IdpDok_RxmwCnnR3tfiPNBI2ssxqhZyAzgJTND62Og5oB58DJHRpDlkJCgNARGhOSpgnN8uwBTUI4EAKM5XSM_tY2au-7Nhpnsatx_NZ47ayRuHTyiI29OEsv1PlobL8ucYq_tNRtdL4XoWtiGM5WzoZoYhfNqScMVCsa8ysuYGEV3nbeBrzRJ-1Fgxc2in2fEy7f0eFN9M7u8eJmPqL7WjRBP93mFG3fXrerj6T8fF-vFmUioYCYqEKCfuGqYFrkUmaMElmnuSJ6p4FxXlBCMk5zULtcMaFozghNC6YUpbzO6BTNr1jpXQhe11XrzY_w5wpINfRaDb0Oqrr2Sv8BrRlxBw
CitedBy_id crossref_primary_10_1371_journal_pone_0173486
crossref_primary_10_1016_j_fbr_2015_11_001
crossref_primary_10_1371_journal_pone_0260173
crossref_primary_10_1096_fj_202001729RR
crossref_primary_10_1016_j_bmc_2015_03_026
crossref_primary_10_1016_j_jbc_2021_100329
crossref_primary_10_1517_14728222_2013_827664
crossref_primary_10_1007_s11064_013_1126_9
crossref_primary_10_1016_j_jmb_2013_04_011
crossref_primary_10_1111_febs_15829
Cites_doi 10.1016/0006-291X(92)91187-U
10.1074/jbc.M107024200
10.1021/jm9002445
10.1016/j.tips.2009.02.006
10.1073/pnas.0435715100
10.1124/mol.106.029470
10.1515/BC.2004.109
10.1038/nchembio.634
10.1515/BC.2011.095
10.1529/biophysj.107.117648
10.1016/j.tips.2007.06.003
10.1074/jbc.M111675200
10.1074/jbc.C300443200
10.1124/jpet.109.163220
10.1002/cmdc.200600134
10.1016/j.jmb.2004.07.044
10.1074/jbc.273.17.10445
10.1016/j.cellsig.2007.01.022
10.1074/jbc.M103747200
10.1038/nature09648
10.1016/j.tips.2003.10.003
10.1016/j.jmb.2008.05.022
10.1074/jbc.271.50.32366
10.1074/jbc.M111.256909
10.1038/nrd2199
10.1016/j.tibs.2011.06.003
10.1021/bi0155091
10.1002/1096-987X(200009)21:12<1049::AID-JCC3>3.0.CO;2-F
10.1021/bi027224+
10.1126/stke.2005/308/cm10
10.1073/pnas.1834556100
10.1124/pr.57.1.2
10.1126/science.289.5480.739
10.1099/ijs.0.01472-0
10.1124/pr.110.003350
10.1124/mol.55.1.92
10.1073/pnas.0230374100
10.1038/nature08144
10.1111/j.1742-4658.2009.07071.x
10.1210/en.2002-0135
10.1126/scisignal.2001707
10.1002/j.1460-2075.1996.tb00726.x
10.1093/nar/gkg500
10.1128/MCB.20.18.6837-6848.2000
10.1007/s00018-010-0368-9
10.1124/mol.56.1.175
10.1111/j.1476-5381.2012.02054.x
ContentType Journal Article
DBID AAYXX
CITATION
DOI 10.1124/jpet.112.199190
DatabaseName CrossRef
DatabaseTitle CrossRef
DeliveryMethod fulltext_linktorsrc
Discipline Pharmacy, Therapeutics, & Pharmacology
EISSN 1521-0103
EndPage 95
ExternalDocumentID 10_1124_jpet_112_199190
GroupedDBID ---
-~X
.55
.GJ
0R~
18M
2WC
3O-
4.4
53G
5GY
5RE
5VS
8WZ
A6W
AAJMC
AAYOK
AAYXX
ABCQX
ABIVO
ABJNI
ABOCM
ABSQV
ACGFO
ACGFS
ACNCT
ADBBV
ADCOW
ADIYS
AENEX
AERNN
AFFNX
AFHIN
AFOSN
AGFXO
AI.
ALMA_UNASSIGNED_HOLDINGS
BAWUL
BTFSW
CITATION
CS3
DIK
DU5
E3Z
EBS
EJD
F5P
F9R
FDB
GX1
H13
HZ~
INIJC
KQ8
L7B
LSO
MJL
MVM
O9-
OHT
OK1
P2P
R.V
R0Z
RHF
RHI
RPT
TR2
UQL
VH1
W2D
W8F
WH7
WOQ
X7M
YBU
YHG
YQT
ZGI
ZXP
ID FETCH-LOGICAL-c171t-d7c1e89d74ea6cc5430cf26d0ebe1499730059361db6d4ad36403274dd339f53
ISSN 0022-3565
IngestDate Fri Dec 06 03:33:30 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c171t-d7c1e89d74ea6cc5430cf26d0ebe1499730059361db6d4ad36403274dd339f53
PageCount 11
ParticipantIDs crossref_primary_10_1124_jpet_112_199190
PublicationCentury 2000
PublicationDate 2013-01-00
PublicationDateYYYYMMDD 2013-01-01
PublicationDate_xml – month: 01
  year: 2013
  text: 2013-01-00
PublicationDecade 2010
PublicationTitle The Journal of pharmacology and experimental therapeutics
PublicationYear 2013
References 2019081411464757000_344.1.85.30
2019081411464757000_344.1.85.4
2019081411464757000_344.1.85.16
2019081411464757000_344.1.85.38
2019081411464757000_344.1.85.5
2019081411464757000_344.1.85.15
2019081411464757000_344.1.85.37
2019081411464757000_344.1.85.2
2019081411464757000_344.1.85.14
2019081411464757000_344.1.85.3
2019081411464757000_344.1.85.13
2019081411464757000_344.1.85.35
2019081411464757000_344.1.85.8
2019081411464757000_344.1.85.12
2019081411464757000_344.1.85.34
2019081411464757000_344.1.85.9
2019081411464757000_344.1.85.11
2019081411464757000_344.1.85.33
2019081411464757000_344.1.85.6
2019081411464757000_344.1.85.10
2019081411464757000_344.1.85.32
2019081411464757000_344.1.85.7
2019081411464757000_344.1.85.31
2019081411464757000_344.1.85.19
2019081411464757000_344.1.85.17
Jacoby (2019081411464757000_344.1.85.18) 2006; 1
2019081411464757000_344.1.85.39
2019081411464757000_344.1.85.41
2019081411464757000_344.1.85.40
2019081411464757000_344.1.85.1
2019081411464757000_344.1.85.27
2019081411464757000_344.1.85.26
2019081411464757000_344.1.85.25
2019081411464757000_344.1.85.47
2019081411464757000_344.1.85.24
2019081411464757000_344.1.85.46
2019081411464757000_344.1.85.23
Scheer (2019081411464757000_344.1.85.36) 1996; 15
2019081411464757000_344.1.85.45
2019081411464757000_344.1.85.44
2019081411464757000_344.1.85.21
2019081411464757000_344.1.85.43
2019081411464757000_344.1.85.20
2019081411464757000_344.1.85.42
Leschner (2019081411464757000_344.1.85.22) 2011; 392
2019081411464757000_344.1.85.29
2019081411464757000_344.1.85.28
References_xml – ident: 2019081411464757000_344.1.85.17
  doi: 10.1016/0006-291X(92)91187-U
– ident: 2019081411464757000_344.1.85.8
  doi: 10.1074/jbc.M107024200
– ident: 2019081411464757000_344.1.85.16
  doi: 10.1021/jm9002445
– ident: 2019081411464757000_344.1.85.26
  doi: 10.1016/j.tips.2009.02.006
– ident: 2019081411464757000_344.1.85.14
  doi: 10.1073/pnas.0435715100
– ident: 2019081411464757000_344.1.85.33
  doi: 10.1124/mol.106.029470
– ident: 2019081411464757000_344.1.85.10
  doi: 10.1515/BC.2004.109
– ident: 2019081411464757000_344.1.85.19
  doi: 10.1038/nchembio.634
– volume: 392
  start-page: 1021
  year: 2011
  ident: 2019081411464757000_344.1.85.22
  article-title: Fever-like temperature modification differentially affects in vitro signaling of bradykinin B(1) and B(2) receptors
  publication-title: Biol Chem
  doi: 10.1515/BC.2011.095
  contributor:
    fullname: Leschner
– ident: 2019081411464757000_344.1.85.5
  doi: 10.1529/biophysj.107.117648
– ident: 2019081411464757000_344.1.85.20
  doi: 10.1016/j.tips.2007.06.003
– ident: 2019081411464757000_344.1.85.38
  doi: 10.1074/jbc.M111675200
– ident: 2019081411464757000_344.1.85.1
  doi: 10.1074/jbc.C300443200
– ident: 2019081411464757000_344.1.85.37
  doi: 10.1124/jpet.109.163220
– volume: 1
  start-page: 761
  year: 2006
  ident: 2019081411464757000_344.1.85.18
  article-title: The 7 TM G-protein-coupled receptor target family
  publication-title: ChemMedChem
  doi: 10.1002/cmdc.200600134
  contributor:
    fullname: Jacoby
– ident: 2019081411464757000_344.1.85.27
  doi: 10.1016/j.jmb.2004.07.044
– ident: 2019081411464757000_344.1.85.3
  doi: 10.1074/jbc.273.17.10445
– ident: 2019081411464757000_344.1.85.41
  doi: 10.1016/j.cellsig.2007.01.022
– ident: 2019081411464757000_344.1.85.4
  doi: 10.1074/jbc.M103747200
– ident: 2019081411464757000_344.1.85.30
  doi: 10.1038/nature09648
– ident: 2019081411464757000_344.1.85.47
  doi: 10.1016/j.tips.2003.10.003
– ident: 2019081411464757000_344.1.85.44
  doi: 10.1016/j.jmb.2008.05.022
– ident: 2019081411464757000_344.1.85.6
  doi: 10.1074/jbc.271.50.32366
– ident: 2019081411464757000_344.1.85.13
  doi: 10.1074/jbc.M111.256909
– ident: 2019081411464757000_344.1.85.28
  doi: 10.1038/nrd2199
– ident: 2019081411464757000_344.1.85.40
  doi: 10.1016/j.tibs.2011.06.003
– ident: 2019081411464757000_344.1.85.42
  doi: 10.1021/bi0155091
– ident: 2019081411464757000_344.1.85.46
  doi: 10.1002/1096-987X(200009)21:12<1049::AID-JCC3>3.0.CO;2-F
– ident: 2019081411464757000_344.1.85.24
  doi: 10.1021/bi027224+
– ident: 2019081411464757000_344.1.85.39
  doi: 10.1126/stke.2005/308/cm10
– ident: 2019081411464757000_344.1.85.45
  doi: 10.1073/pnas.1834556100
– ident: 2019081411464757000_344.1.85.21
  doi: 10.1124/pr.57.1.2
– ident: 2019081411464757000_344.1.85.29
  doi: 10.1126/science.289.5480.739
– ident: 2019081411464757000_344.1.85.34
  doi: 10.1099/ijs.0.01472-0
– ident: 2019081411464757000_344.1.85.35
  doi: 10.1124/pr.110.003350
– ident: 2019081411464757000_344.1.85.23
  doi: 10.1124/mol.55.1.92
– ident: 2019081411464757000_344.1.85.43
  doi: 10.1073/pnas.0230374100
– ident: 2019081411464757000_344.1.85.32
  doi: 10.1038/nature08144
– ident: 2019081411464757000_344.1.85.12
  doi: 10.1111/j.1742-4658.2009.07071.x
– ident: 2019081411464757000_344.1.85.15
  doi: 10.1210/en.2002-0135
– ident: 2019081411464757000_344.1.85.25
  doi: 10.1126/scisignal.2001707
– volume: 15
  start-page: 3566
  year: 1996
  ident: 2019081411464757000_344.1.85.36
  article-title: Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation
  publication-title: EMBO J
  doi: 10.1002/j.1460-2075.1996.tb00726.x
  contributor:
    fullname: Scheer
– ident: 2019081411464757000_344.1.85.9
  doi: 10.1093/nar/gkg500
– ident: 2019081411464757000_344.1.85.7
  doi: 10.1128/MCB.20.18.6837-6848.2000
– ident: 2019081411464757000_344.1.85.2
  doi: 10.1007/s00018-010-0368-9
– ident: 2019081411464757000_344.1.85.31
  doi: 10.1124/mol.56.1.175
– ident: 2019081411464757000_344.1.85.11
  doi: 10.1111/j.1476-5381.2012.02054.x
SSID ssj0014463
Score 2.1900914
SourceID crossref
SourceType Aggregation Database
StartPage 85
Title Interruption of the Ionic Lock in the Bradykinin B 2 Receptor Results in Constitutive Internalization and Turns Several Antagonists into Strong Agonists
Volume 344
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwFLbKeOEFcRWMi84DmpC6jCR2kuVxQ4ypbGiIIPZWJbEzTZS0ahOk8Uv4l_wFzrGdxC0gDV4iy3WsNOfLuflcGHsh46TMq0J6sip9T0QpfnNRrLwEsZNUBRoIutnE6fv4-JOYnEfno9FPJ2qpbYq98vsf80r-h6o4h3SlLNl_oGy_KU7gGOmLV6QwXq9FY-3OW7aLTuvTkZC6pc0JsrkuhJGOy6--UCOI8eE4JEVRLdDSJs99O2tWNu_PxAxQHJF1Es5shqY-XsjwaVbIWL6RC4sqDuQXc6q5S3ej9vqRHOoX4wM76Wq8Q-6Z1noXQ6lsU_lprcWAkw3W6_onCg1wm5YzyVdfL3s4fyYhsewC1N7O8d7-tyOF8t5mOU5UPRwGoCRqrdv8lPI8Z67fg3pQ9H4PNw_BdJrYU5Z9h7TI5y5_56bA5BqQDbfejxy5b3p9_i5RQkESBU0YGlNyZ2D6m67X7t6QqX2ko7axQjGlDWg0NRvcYDepciM1e3j3YTj2Qtuc9-Xt8a_ZWlS4wauNJ3DUKEcfyu6w25akcGBQeZeNVH2P7ZwZ8l7tQuaQchd24Mwh_H32w4UuzCtAyoOGLhB04bLWMwN04RBC6KALFrq0zIUubEAXEGCgoQsWuuBAFwi6YKALHXQfsOzoTfb62LNNQrwS-UjjyaQM1H4qE6HyuCwjwf2yCmPpI3dC6z_V_RhSHgeyiKXIJY-Fz8NESMl5WkX8Iduq57V6xCAIigpXqpBHhZCqyDkqd0WMMjCXKoiTx-xl98qnC1MKZvoX8m5ff-kTdmtA91O21Sxb9Qz13KZ4rrHxC4lJsp4
link.rule.ids 314,780,784,27924,27925
linkProvider Colorado Alliance of Research Libraries
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Interruption+of+the+Ionic+Lock+in+the+Bradykinin+B+2+Receptor+Results+in+Constitutive+Internalization+and+Turns+Several+Antagonists+into+Strong+Agonists&rft.jtitle=The+Journal+of+pharmacology+and+experimental+therapeutics&rft.au=Leschner%2C+Jasmin&rft.au=Wennerberg%2C+Goeran&rft.au=Feierler%2C+Jens&rft.au=Bermudez%2C+Marcel&rft.date=2013-01-01&rft.issn=0022-3565&rft.eissn=1521-0103&rft.volume=344&rft.issue=1&rft.spage=85&rft.epage=95&rft_id=info:doi/10.1124%2Fjpet.112.199190&rft.externalDBID=n%2Fa&rft.externalDocID=10_1124_jpet_112_199190
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-3565&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-3565&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-3565&client=summon