Beyond transfusions and transplants: genomic innovations rewriting the narrative of thalassemia

• Published in: Annals of hematology
• Main Authors: Shi, Liangbin, Yan, Xili, Xia, Yanwei, Zhao, Yingdi, Zhu, Xiuling, Li, Qiang, Xu, Zhiliang
• Format: Journal Article
• Language: English
• Published: Germany 16.08.2025
• Subjects: Thalassemia; Diagnosis; Gene editing; Molecular mechanisms

Thalassemia is a globally prevalent inherited blood disorder that usually leads to severe complications and even premature death due to impaired hemoglobin synthesis. The conventional treatment approach encompasses a range of interventions, including red blood cell transfusions, iron chelation thera...