Exploiting metal-free atom transfer radical polymerization for fabrication of styrene-maleic acid polymer-brush grafting chromatographic stationary phase and its separation performances for phospholipids

• Published in: Analytical and bioanalytical chemistry
• Main Authors: Yang, Ruilin, Wang, Ping, Guan, Xinhui, Gu, Xiaofei, Qiao, Xiaoqiang
• Format: Journal Article
• Language: English
• Published: Germany 09.08.2025
• Subjects: Styrene-maleic acid copolymer; Phospholipids; Polymer-brush; Metal-free atom transfer radical polymerization; Chromatographic stationary phase

Phospholipids have been considered biomarkers for diagnosing many diseases in recent years. However, the isolation and analysis of phospholipids still face many difficulties. Styrene-maleic acid (SMA) copolymer is currently considered suitable for the separation and analysis of phospholipids due to...