Prediction of pulmonary air leak after lobectomies

• Published in: Vestnik hirurgii im. I.I. Grekova Vol. 181; no. 1; pp. 33 - 40
• Main Authors: Akopov, A. L., Agishev, A. S., Mishra, R. P., Kovalev, M. G., Parshin, E. V., Dvoreckiy, S. Yu, Zaripova, Z. A., Rabik, Yu. D., Skvortsova, R. D., Obukhova, A. A.
• Format: Journal Article
• Language: English; Russian
• Published: Pavlov First Saint Petersburg State Medical University 01.09.2022
• Subjects: air leak; lobectomy; preoperative prognosis; respiratory function
• ISSN: 0042-4625; 2686-7370
• DOI: 10.24884/0042-4625-2022-181-1-33-40

The OBJECTIVE was to identify prognostic factors of long-term air leak after lobectomies based on the analysis of the main preoperative and surgical clinical and functional indicators. METHODS AND MATERIALS. A retrospective study included 71 patients who underwent lung resection in the volume of lobectomy for lung cancer. The patients were divided into three groups - group 1 (n=42, 59 %) - air leak through the drains stopped within a day after surgery; group 2 (n=10, 14 %) - the duration of air leak from the pleural cavity from 1 to 5 days; group 3 (n=19, 27 %) the duration of air leak more than 5 days after surgery. RESULTS. The average values of the main clinical, surgical and functional indicators, such as the frequency of concomitant COPD, the severity of its course, smoking status, access (thoracotomy / thoracoscopy) in the three groups were almost the same. The difference in the average value of DLCO was characterized by the greatest tendency to reliability: the longer the pulmonary air leak was, the lower the values of this indicator turned out to be. Correlation analysis revealed a noticeable feedback between the long-term pulmonary air leak and the preoperative level of FEV1 (r=-0.59), a direct relationship between the level of FEV1 and DLCO (r=0.51), as well as a noticeable feedback between the long-term pulmonary air leak and the level of DLCO (r=-0.61) and a direct moderate relationship between the pulmonary air leak and the time spent on the stair climbing test (r=0.38). CONCLUSIONS. The combination of a low level of FEV1, a low level of DLCO and a long duration of the stair climbing test makes it possible to assess the risk of prolonged pulmonary air leak as significant and take this into account during the surgical intervention.