Variations in CCR5, but not HFE, ELMO1, or SLC12A3, are associated with susceptibility to kidney disease in north Indian individuals with type 2 diabetes CCR5变异而不是HFE、ELMO1或者SLC12A3变异与印度北部的2型糖尿病患者的肾病易感性相关

• Published in: Journal of diabetes Vol. 6; no. 6; pp. 547 - 555
• Main Authors: Yadav, Ashok K., Kumar, Vinod, Dutta, Pinaki, Bhansali, Anil, Jha, Vivekanand
• Format: Journal Article
• Language: English
• Published: Blackwell Publishing Ltd 01.11.2014
• Subjects: diabetic nephropathy; ELMO1; genetics; HFE; SLC12A3; type 2 diabetes; 关键词：糖尿病肾病，ELMO1，遗传学，HFE，SLC12A3，2型糖尿病

Background Diabetic nephropathy (DN), the leading cause of end‐stage renal disease worldwide, may have a genetic component. In the present study, we investigated variations in a set of genes with susceptibility to DN in a north Indian population. Methods Four genes (HFE, ELMO1, SLC12A3, and CCR5) we...