Measles Virus as a Vector Platform for Glioblastoma Immunotherapy (Review)

• Published in: Razrabotka i registraciâ lekarstvennyh sredstv (Online) Vol. 11; no. 1; pp. 51 - 58
• Main Authors: Nikolaeva, E. Yu, Shchetinina, Yu. R., Shokhin, I. E., Zverev, V. V., Svitich, O. A., Susova, O. Yu, Mitrofanov, A. A., Ammour, Yu. I.
• Format: Journal Article
• Language: English; Russian
• Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 23.02.2022
• Subjects: виротерапия; вирус кори; иммунотерапия; онколитические вирусы; рецептор cd46

Introduction. Oncolytic virotherapy is one of the approaches in immunotherapy of solid brain tumors. Measles virus vaccine strains are prospective agents for the therapy of cancers such as neuroblastoma, mesothelioma, and glioblastoma multiforme. The hyperexpression of the CD46 and other receptors o...