Optimization of the object recognition assay to test mouse cognition

• Published in: Alzheimer's & dementia Vol. 20; no. S1
• Main Authors: Sambamurti, Kumar, Crowder, Dallas, Pappolla, Miguel A, Shah, Suhua, Fan, Hongkuan, Lahiri, Debomoy K., Greig, Nigel H, Kanthasamy, Anumantha
• Format: Journal Article
• Language: English
• Published: Hoboken John Wiley and Sons Inc 01.12.2024
• Subjects: Basic Science and Pathogenesis

Background Alzheimer’s disease (AD) has traditionally been recognized as progressive dementia with brain deposits of amyloid (Aβ) and Tau (MAPT) proteins starting 20 and 10 years before the onset of clinical symptoms. Aggregation and deposition of Aβ and Tau proteins have been successfully studied i...