YM-216391, a Novel Cytotoxic Cyclic Peptide from Streptomyces nobilis

• Published in: Journal of antibiotics Vol. 58; no. 1; p. 32
• Main Authors: Sohda, Kin-ya, Hiramoto, Masashi, Suzumura, Ken-ichi, Takebayashi, Yukihiro, Suzuki, Ken-ichi, Tanaka, Akihiro
• Format: Journal Article
• Language: English
• Published: Tokyo Nature Publishing Group 01.01.2005
• Subjects: Amino acids; Liquid chromatography

AbstractYM-216391, a novel cytotoxic cyclic peptide, has been isolated from the cultured mycelium of Streptomyces nobilis JCM 4274. The planar structure of YM-216391 was assigned on the basis of 1D and 2D NMR spectroscopic techniques. The absolute configuration of the amino acid residues in YM-21639...