Erdheim-Chester disease detected with 99MTC MDP bone SPECT/CT

Erdheim-Chester disease (ECD) is a rare non-Langerhans’ cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist. The lesions...

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Bibliographic Details
Published inJournal of the Belgian Society of Radiology Vol. 95; no. 4; pp. 245 - 248
Main Authors G Ceulemans, M Keyaerts, L Verbruggen, A Hoorens, C Boulet, D Verdries, M De Maeseneer, B Ilsen, H Everaert
Format Journal Article
LanguageEnglish
Published Ubiquity Press 01.07.2012
Subjects
Lipogranulomatosis
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Summary:Erdheim-Chester disease (ECD) is a rare non-Langerhans’ cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist. The lesions consist of lipid-storing CD 68 +/ CD 1a – non- Langerhans’ cell histiocytes, most frequently localized in bone but also involving multiple organ systems in the body. We present a case report in which the diagnosis of ECD was established with 99mTc MDP bone SPECT/CT.
ISSN:2514-8281
DOI:10.5334/jbr-btr.630