Management of Kidney Disease with Sickle Cell Disease

• Published in: Journal of the American Society of Nephrology
• Main Authors: Abbasi, Momen, Srivastava, Anand, Saraf, Santosh L.
• Format: Journal Article
• Language: English
• Published: United States 26.06.2025
• Subjects: glomerular diseases; anemia; hyperfiltration; kidney transplantation

Sickle cell disease is the most common inherited blood cell disorder in the United States. Vaso-occlusion and hemolysis are hallmark features of sickle cell disease that may lead to kidney damage through endothelial dysfunction and oxidative and inflammatory stress. Manifestations of sickle cell dis...