Management of Candida Urinary Tract Infection in the Elderly

• Published in: Urogenital tract infection Vol. 14; no. 2; pp. 33 - 41
• Main Authors: Kim, Sang Jin, Ryu, Jae Hyun, Kim, Yun Beom, Yang, Seung Ok
• Format: Journal Article
• Language: English
• Published: 대한요로생식기감염학회 01.08.2019
• Subjects: 비뇨기과학
• ISSN: 2465-8243; 2465-8510
• DOI: 10.14777/uti.2019.14.2.33

Candida urinary tract infections in elderly patients are becoming increasingly common. The risk factors for the development of candiduria include old age, use of broad-spectrum antibiotics, corticosteroids and indwelling urethral catheters, as well as diabetes mellitus, urological abnormalities, and hematological malig-nancies. The presence of signs and symptoms of infection are unusual, and the intensity of fungal growth in culture does not correlate with the outcome. Elderly patients often present with atypical signs and symptoms of infection. Careful assessment of the patient’s clinical status should be undertaken before treatment is initiated. The indications for antifungal therapy are the same for older and younger individuals, and the initial antifungal therapy should be selected based on the infecting organism and local epidemiology. Fluconazole is the mainstay of treat-ment. On the other hand, Candida glabrata is more common in elderly patients and is often refractory to fluconazole therapy. The selection of drug therapy for elderly patients should consider the comorbidities, risk of drug-drug interactions, and dose adjustment for physiological function. KCI Citation Count: 0