Selective binding interactions of deramciclane to the genetic variants of human α1-acid glycoprotein

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Published inBiochimica et biophysica acta. General subjects Vol. 1800; no. 3; pp. 367 - 372
Main Authors Fitos, Ilona, Visy, Júlia, Simonyi, Miklós, Mády, György, Zsila, Ferenc
Format Journal Article
LanguageEnglish
Published 01.03.2010
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ISSN0304-4165
DOI10.1016/j.bbagen.2009.08.006

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Author Fitos, Ilona
Mády, György
Visy, Júlia
Simonyi, Miklós
Zsila, Ferenc
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Cites_doi 10.1002/(SICI)1520-636X(1999)11:9<689::AID-CHIR4>3.0.CO;2-X
10.1016/j.euroneuro.2005.03.002
10.1016/j.carres.2003.10.016
10.1248/cpb.36.4958
10.1016/j.bbagen.2006.08.015
10.1111/j.1365-2125.1993.tb04224.x
10.1016/0006-2952(92)90175-I
10.1002/(SICI)1098-2299(199704)40:4<333::AID-DDR7>3.0.CO;2-K
10.1124/dmd.105.003764
10.1007/s00216-008-2518-6
10.1016/j.bbapap.2005.12.006
10.1016/j.bcp.2003.09.039
10.1016/j.jmb.2008.09.020
10.1016/0378-4347(93)80289-G
10.1023/B:PHAM.0000041461.93787.6b
10.2174/138161206776055967
10.1248/cpb.38.1688
10.1007/BF00210681
10.1023/A:1015880327911
10.1016/j.bbapap.2008.03.015
10.1016/0006-2952(91)90029-5
10.1021/bi0600087
10.1002/j.1460-2075.1987.tb02503.x
10.1021/jm030843b
10.1081/DMR-100104402
10.1016/S0040-4020(01)82798-8
10.1007/s004390050378
10.1124/mol.54.1.129
10.1016/S0006-2952(02)01521-6
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References Gacsályi (10.1016/j.bbagen.2009.08.006_bib15) 1997; 40
Fitos (10.1016/j.bbagen.2009.08.006_bib11) 2006; 1760
Miyoshi (10.1016/j.bbagen.2009.08.006_bib27) 1992; 9
Calvo (10.1016/j.bbagen.2009.08.006_bib4) 2006; 12
Kremer (10.1016/j.bbagen.2009.08.006_bib1) 1988; 40
Fitos (10.1016/j.bbagen.2009.08.006_bib22) 2004; 67
Tomei (10.1016/j.bbagen.2009.08.006_bib6) 1989; 84
Yuasa (10.1016/j.bbagen.2009.08.006_bib7) 1997; 99
Hervé (10.1016/j.bbagen.2009.08.006_bib9) 1998; 54
Israili (10.1016/j.bbagen.2009.08.006_bib2) 2001; 33
Schönfeld (10.1016/j.bbagen.2009.08.006_bib13) 2008; 384
Monostory (10.1016/j.bbagen.2009.08.006_bib18) 2005; 33
Naukkarinen (10.1016/j.bbagen.2009.08.006_bib16) 2005; 15
Hervé (10.1016/j.bbagen.2009.08.006_bib8) 1993; 615
Johansson (10.1016/j.bbagen.2009.08.006_bib29) 2003; 46
Zsila (10.1016/j.bbagen.2009.08.006_bib31) 2008; 1784
Hutchinson (10.1016/j.bbagen.2009.08.006_bib28) 1969; 25
Visy (10.1016/j.bbagen.2009.08.006_bib17) 1996; 2
Ladányi (10.1016/j.bbagen.2009.08.006_bib14) 1999; 11
Breustedt (10.1016/j.bbagen.2009.08.006_bib20) 2006; 1764
Miyoshi (10.1016/j.bbagen.2009.08.006_bib26) 1992; 43
Otagiri (10.1016/j.bbagen.2009.08.006_bib21) 1991; 42
Maruyama (10.1016/j.bbagen.2009.08.006_bib19) 1990; 38
Zsila (10.1016/j.bbagen.2009.08.006_bib24) 2003; 65
Budai (10.1016/j.bbagen.2009.08.006_bib3) 2009; 393
Hervé (10.1016/j.bbagen.2009.08.006_bib10) 1993; 36
Albani (10.1016/j.bbagen.2009.08.006_bib23) 2004; 339
Dente (10.1016/j.bbagen.2009.08.006_bib5) 1987; 6
Asher (10.1016/j.bbagen.2009.08.006_bib30) 2006; 45
Katsuki (10.1016/j.bbagen.2009.08.006_bib12) 2004; 21
Otagiri (10.1016/j.bbagen.2009.08.006_bib25) 1988; 36
References_xml – volume: 2
  start-page: 315
  year: 1996
  ident: 10.1016/j.bbagen.2009.08.006_bib17
  article-title: Plasma protein binding of deramciclane in different species
  publication-title: Pharm. Sci.
– volume: 11
  start-page: 689
  year: 1999
  ident: 10.1016/j.bbagen.2009.08.006_bib14
  article-title: Stereochemistry and enantiomeric purity of a novel anxiolytic agent, deramciclane fumarate
  publication-title: Chirality
  doi: 10.1002/(SICI)1520-636X(1999)11:9<689::AID-CHIR4>3.0.CO;2-X
– volume: 15
  start-page: 617
  year: 2005
  ident: 10.1016/j.bbagen.2009.08.006_bib16
  article-title: Deramciclane in the treatment of generalized anxiety disorder: a placebo-controlled, double-blind, dose-finding study
  publication-title: Eur. Neuropsychopharmacology
  doi: 10.1016/j.euroneuro.2005.03.002
– volume: 339
  start-page: 607
  year: 2004
  ident: 10.1016/j.bbagen.2009.08.006_bib23
  article-title: Tertiary structure of human alpha1-acid glycoprotein (orosomucoid). Straightforward fluorescence experiments revealing the presence of a binding pocket
  publication-title: Carbohydr. Res.
  doi: 10.1016/j.carres.2003.10.016
– volume: 36
  start-page: 4958
  year: 1988
  ident: 10.1016/j.bbagen.2009.08.006_bib25
  article-title: Study on the binding of dicumarol to α1-acid glycoprotein using circular dichroism spectroscopy
  publication-title: Chem. Pharm. Bull.
  doi: 10.1248/cpb.36.4958
– volume: 1760
  start-page: 1704
  year: 2006
  ident: 10.1016/j.bbagen.2009.08.006_bib11
  article-title: Selective binding of imatinib to the genetic variants of human alpha1-acid glycoprotein
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbagen.2006.08.015
– volume: 36
  start-page: 241
  year: 1993
  ident: 10.1016/j.bbagen.2009.08.006_bib10
  article-title: Evidence for differences in the binding of drugs to the two main genetic variants of human alpha 1-acid glycoprotein
  publication-title: Br. J. Clin. Pharmacol.
  doi: 10.1111/j.1365-2125.1993.tb04224.x
– volume: 43
  start-page: 2161
  year: 1992
  ident: 10.1016/j.bbagen.2009.08.006_bib26
  article-title: Further characterization of reversal of signs of induced Cotton effects of dicumarol derivatives-α1-acid glycoprotein systems by protriptyline
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/0006-2952(92)90175-I
– volume: 40
  start-page: 333
  year: 1997
  ident: 10.1016/j.bbagen.2009.08.006_bib15
  article-title: Receptor binding profile and anxiolytic activity of deramciclane (EGIS-3886) in animal models
  publication-title: Drug Dev. Res.
  doi: 10.1002/(SICI)1098-2299(199704)40:4<333::AID-DDR7>3.0.CO;2-K
– volume: 33
  start-page: 1708
  year: 2005
  ident: 10.1016/j.bbagen.2009.08.006_bib18
  article-title: Biotransformation of deramciclane in primary hepatocytes of rat, mouse, rabbit, dog, and human
  publication-title: Drug Metab. Disp.
  doi: 10.1124/dmd.105.003764
– volume: 393
  start-page: 991
  year: 2009
  ident: 10.1016/j.bbagen.2009.08.006_bib3
  article-title: Investigation of genetic variants of α1-acid glycoprotein by ultra-performance liquid chromatography-mass spectrometry
  publication-title: Anal. Bioanal. Chem.
  doi: 10.1007/s00216-008-2518-6
– volume: 1764
  start-page: 161
  year: 2006
  ident: 10.1016/j.bbagen.2009.08.006_bib20
  article-title: Comparative ligand-binding analysis of ten human lipocalins
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbapap.2005.12.006
– volume: 67
  start-page: 679
  year: 2004
  ident: 10.1016/j.bbagen.2009.08.006_bib22
  article-title: Specific ligand binding on genetic variants of human alpha1-acid glycoprotein studied by circular dichroism spectroscopy
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2003.09.039
– volume: 384
  start-page: 393
  year: 2008
  ident: 10.1016/j.bbagen.2009.08.006_bib13
  article-title: The 1.8-Å crystal structure of α1-acid glycoprotein (orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin
  publication-title: J. Mol. Biol.
  doi: 10.1016/j.jmb.2008.09.020
– volume: 615
  start-page: 47
  year: 1993
  ident: 10.1016/j.bbagen.2009.08.006_bib8
  publication-title: J. Chromatogr.
  doi: 10.1016/0378-4347(93)80289-G
– volume: 21
  start-page: 1648
  year: 2004
  ident: 10.1016/j.bbagen.2009.08.006_bib12
  article-title: Tryptophan residues play an important role in the extraordinarily high-affinity binding interaction of UCN-01 to human α1-acid glycoprotein
  publication-title: Pharm. Res.
  doi: 10.1023/B:PHAM.0000041461.93787.6b
– volume: 12
  start-page: 977
  year: 2006
  ident: 10.1016/j.bbagen.2009.08.006_bib4
  article-title: The role of unbound drug in pharmacokinetics/pharmacodynamics and therapy
  publication-title: Curr. Pharm. Design
  doi: 10.2174/138161206776055967
– volume: 38
  start-page: 1688
  year: 1990
  ident: 10.1016/j.bbagen.2009.08.006_bib19
  article-title: Characterization of drug binding sites on alpha 1-acid glycoprotein
  publication-title: Chem. Pharm. Bull. (Tokyo)
  doi: 10.1248/cpb.38.1688
– volume: 84
  start-page: 89
  year: 1989
  ident: 10.1016/j.bbagen.2009.08.006_bib6
  article-title: Use of transgenic mice for the characterization of human alpha 1-acid glycoprotein (orosomucoid) variants
  publication-title: Hum. Genet.
  doi: 10.1007/BF00210681
– volume: 9
  start-page: 845
  year: 1992
  ident: 10.1016/j.bbagen.2009.08.006_bib27
  article-title: Reversal of signs of induced cotton effects of dicumarol-alpha 1-acid glycoprotein systems by phenothiazine neuroleptics through ternary complexation
  publication-title: Pharm. Res.
  doi: 10.1023/A:1015880327911
– volume: 1784
  start-page: 1106
  year: 2008
  ident: 10.1016/j.bbagen.2009.08.006_bib31
  article-title: Organogold complexes probe a large β-barrel cavity for human serum α1-acid glycoprotein
  publication-title: Biochim. Biophys. Acta
  doi: 10.1016/j.bbapap.2008.03.015
– volume: 42
  start-page: 729
  year: 1991
  ident: 10.1016/j.bbagen.2009.08.006_bib21
  article-title: Effects of tricyclic drug on induced circular dichroism spectra of dicumarol bound to α1-acid glycoprotein
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/0006-2952(91)90029-5
– volume: 45
  start-page: 6372
  year: 2006
  ident: 10.1016/j.bbagen.2009.08.006_bib30
  article-title: The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol
  publication-title: Biochemistry
  doi: 10.1021/bi0600087
– volume: 6
  start-page: 2289
  year: 1987
  ident: 10.1016/j.bbagen.2009.08.006_bib5
  article-title: Structure and expression of the genes coding for human α1-acid glycoprotein
  publication-title: EMBO J.
  doi: 10.1002/j.1460-2075.1987.tb02503.x
– volume: 46
  start-page: 4009
  year: 2003
  ident: 10.1016/j.bbagen.2009.08.006_bib29
  article-title: Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form
  publication-title: J. Med. Chem.
  doi: 10.1021/jm030843b
– volume: 33
  start-page: 161
  year: 2001
  ident: 10.1016/j.bbagen.2009.08.006_bib2
  article-title: Human alpha-1-glycoprotein and its interactions with drugs
  publication-title: Drug. Metab. Rev.
  doi: 10.1081/DMR-100104402
– volume: 40
  start-page: 1
  year: 1988
  ident: 10.1016/j.bbagen.2009.08.006_bib1
  article-title: Drug binding to human alpha-1-acid glycoprotein in health and disease
  publication-title: Pharmacol. Rev.
– volume: 25
  start-page: 2531
  year: 1969
  ident: 10.1016/j.bbagen.2009.08.006_bib28
  article-title: The structure of dicoumarol and related compounds
  publication-title: Tetrahedron
  doi: 10.1016/S0040-4020(01)82798-8
– volume: 99
  start-page: 393
  year: 1997
  ident: 10.1016/j.bbagen.2009.08.006_bib7
  article-title: Human orosomucoid polymorphism: molecular basis of the three common ORM1 alleles, ORM1⁎F1, ORM1⁎F2, and ORM1⁎S
  publication-title: Hum. Genet.
  doi: 10.1007/s004390050378
– volume: 54
  start-page: 129
  year: 1998
  ident: 10.1016/j.bbagen.2009.08.006_bib9
  article-title: Ligand specificity of the genetic variants of human α1-acid glycoprotein: Generation of a three-dimensional quantitative structure-activity relationship model for drug binding to the A variant
  publication-title: Mol. Pharmacol.
  doi: 10.1124/mol.54.1.129
– volume: 65
  start-page: 447
  year: 2003
  ident: 10.1016/j.bbagen.2009.08.006_bib24
  article-title: Probing the binding of the flavonoid, quercetin to human serum albumin by circular dichroism, electronic absorption spectroscopy and molecular modelling methods
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/S0006-2952(02)01521-6
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