Interaction of storage carbohydrates and other cyclic fluxes with central metabolism: A quantitative approach by non-stationary 13 C metabolic flux analysis - Suarez-Mendez, C.A.; Hanemaaijer, M.; ten Pierick, Angela; Wolters, J.C.; Heijnen, J.J.; Wahl, S.A. (Metabolic engineering communications, 2016)
Keywords: GLU, glutamate; PYK, pyruvate kinase; T6P, trehalose-6-phosphate; FBP, fructose-1,6-bis-phosphate; Flux estimation; PGM, phosphoglucomutase; LEU, leucine; FUM, fumarate; GLN, glutamine; PFK, 6-phosphofructokinase; X5P, xylulose-5-phosphate; GLY, glycine; E4P, erythrose-4-phosphate; S7P, sedoheptulose-7-phosphate; DO, dissolved oxygen; UDPG, UDP-glucose; OAA, oxaloacetate; MAL, malate; FMH, fumarate hydratase; RPI, ribose-5-phosphate isomerase; ASP, aspartate; PEP, phospho-enol-pyruvate; DHAP, dihydroxy acetone phosphate; PRO, proline; PYR, pyruvate; RPE, ribulose-phosphate 3-epimerase; UTP, uridine-5-triphosphate; TCA, tricarboxylic acid cycle; PPP, pentose phosphate pathway; LYS, lysine; Ribu5P, ribulose-5-phosphate; F6P, fructose-6-phosphate; Rib5P, ribose-5-phosphate; ALA, alanine; TPP, trehalose- phosphatase; Trehalose; α-KG, oxoglutarate; GAP, glyceraldehyde-3-phosphate; Amino acids; PGI, glucose-6-phosphate isomerase; ENO, phosphopyruvate hydratase; 2PG, 2-phosphoglycerate; GAPDH&PGK, glyceraldehyde-3-phosphate dehydrogenase+phosphoglycerate kinase; GPM, phosphoglycerate mutase; 3PG, 3-phosphoglycerate; 6PG, 6-phospho gluconate; CoA, coenzyme-A; G6P, glucose-6-phosphate; TPS, alpha,alpha-trehalose-phosphate synthase; Iso-Cit, isocitrate; PMI, mannose-6-phosphate isomerase; G1P, glucose-1-phosphate; G6PDH, glucose-6-phosphate dehydrogenase; ACO, aconitate hydratase; Glycogen; Non-stationary 13C labeling; OUR, Oxygen uptake rate; SUC, succinate; FBA, fructose-bisphosphate aldolase; SER, serine; METH, methionine; IDMS, Isotope dilution mass spectrometry; UDP, uridine-5-diphosphate; AK, adenylate kinase