Characterization of the Human Lipoprotein Lipase (LPL) Promoter: Evidence of Two cis-Regulatory Regions, LP-α and LP-β, of Importance for the Differentiation-Linked Induction of the LPL Gene during Adipogenesis

• Published in: Molecular and cellular biology Vol. 12; no. 10; pp. 4622 - 4633
• Main Authors: Enerbäck, Sven, Ohlsson, Bertil G., Samuelsson, Lena, Bjursell, Gunnar
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 01.10.1992

When preadipocytes differentiate into adipocytes, several differentiation-linked genes are activated. Lipoprotein lipase (LPL) is one of the first genes induced (luring this process. To investigate early events in adipocyte development, we have focused on the transcriptional activation of the LPL ge...