Comparison of the protective resistance induced by 60Co-irradiated cercariae and schistosomula of the WFFS and NMRI strains of Schistosoma mansoni

• Published in: Journal of helminthology Vol. 59; no. 4; p. 313
• Main Authors: James, E R, Dobinson, A R
• Format: Journal Article
• Language: English
• Published: England 01.12.1985
• Subjects: Animals; Cobalt Radioisotopes; Larva - radiation effects; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Schistosoma mansoni - immunology; Schistosoma mansoni - radiation effects; Schistosomiasis mansoni - prevention & control; Vaccination; Vaccines, Attenuated

Mice, CBA/HT6T6 and C57BL/10, were vaccinated with 1 X 350 or 1 X 500 Schistosoma mansoni cercariae or schistosomula attenuated with 20 or 56 krad 60Co irradiation and challenged with 200 cercariae. Protective resistance against homologous strain challenge was compared using the Winches Farm Field S...