Orbital Venous Malformation

• Published in: Applied radiology (1976) Vol. 49; no. 2; pp. 48 - 48C
• Main Authors: Kent, Amy, Towbin, Richard, Schaefer, Carrie, Kaye, Robin, Jorgensen, Scott, Abruzzo, Todd, Towbin, Alexander, Aria, David
• Format: Journal Article
• Language: English
• Published: Scotch Plains Anderson Publishing Ltd 01.03.2020
• Subjects: Biopsy; Blindness; Children & youth; Deformation mechanisms; Endothelial cells; Ethanol; Lipids; Mutation; Necrosis; Pulmonary fibrosis; Sclerotherapy; Thrombosis; Tumors; Ultrasonic imaging; Water chemistry
• DOI: 10.37549/AR2639
• ISSN: 1879-2898; 0160-9963

[...]infections are common in the orbital and periorbital regions but are rarely confused with a vascular lesion due to the associated clinical features. In a minority of patients, a mutation in the TIE-2 gene has been identified, linking 1.2% of VMs to genetic causes.1,2 Venous malformations involving the face may distend with Valsalva maneuver or positioning the child in a head-down dependent position and can cause deformity, asymmetry, exopthalmus and dental problems. Upon injection, ethanol displaces water molecules and penetrates the lipid bilayer of the cells, which compromises the stable membrane and kills the endothelial cells.3,4 Potential complications with ethanol sclerotherapy include nerve injury with sensory loss and blindness in or around the treated eye, cavernous sinus thrombosis, skin necrosis, renal failure, and cardiopulmonary failure.