Orbital Venous Malformation
[...]infections are common in the orbital and periorbital regions but are rarely confused with a vascular lesion due to the associated clinical features. In a minority of patients, a mutation in the TIE-2 gene has been identified, linking 1.2% of VMs to genetic causes.1,2 Venous malformations involv...
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Published in | Applied radiology (1976) Vol. 49; no. 2; pp. 48 - 48C |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Scotch Plains
Anderson Publishing Ltd
01.03.2020
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Subjects | |
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Abstract | [...]infections are common in the orbital and periorbital regions but are rarely confused with a vascular lesion due to the associated clinical features. In a minority of patients, a mutation in the TIE-2 gene has been identified, linking 1.2% of VMs to genetic causes.1,2 Venous malformations involving the face may distend with Valsalva maneuver or positioning the child in a head-down dependent position and can cause deformity, asymmetry, exopthalmus and dental problems. Upon injection, ethanol displaces water molecules and penetrates the lipid bilayer of the cells, which compromises the stable membrane and kills the endothelial cells.3,4 Potential complications with ethanol sclerotherapy include nerve injury with sensory loss and blindness in or around the treated eye, cavernous sinus thrombosis, skin necrosis, renal failure, and cardiopulmonary failure. |
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AbstractList | [...]infections are common in the orbital and periorbital regions but are rarely confused with a vascular lesion due to the associated clinical features. In a minority of patients, a mutation in the TIE-2 gene has been identified, linking 1.2% of VMs to genetic causes.1,2 Venous malformations involving the face may distend with Valsalva maneuver or positioning the child in a head-down dependent position and can cause deformity, asymmetry, exopthalmus and dental problems. Upon injection, ethanol displaces water molecules and penetrates the lipid bilayer of the cells, which compromises the stable membrane and kills the endothelial cells.3,4 Potential complications with ethanol sclerotherapy include nerve injury with sensory loss and blindness in or around the treated eye, cavernous sinus thrombosis, skin necrosis, renal failure, and cardiopulmonary failure. |
Author | Jorgensen, Scott Towbin, Alexander Abruzzo, Todd Aria, David Kent, Amy Schaefer, Carrie Kaye, Robin Towbin, Richard |
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Cites_doi | 10.3389/fsurg.2017.00027 10.1259/bjr.20130392 10.21037/cdt.2016.11.10 |
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Snippet | [...]infections are common in the orbital and periorbital regions but are rarely confused with a vascular lesion due to the associated clinical features. In a... |
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SubjectTerms | Biopsy Blindness Children & youth Deformation mechanisms Endothelial cells Ethanol Lipids Mutation Necrosis Pulmonary fibrosis Sclerotherapy Thrombosis Tumors Ultrasonic imaging Water chemistry |
Title | Orbital Venous Malformation |
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