Dysplastic nevus (atypical nevus)

Atypical nevum (dysplastic) is considered an important factor associated with increased risk of developing cutaneous melanoma. It is believed that atypical nevi are precursor lesions of cutaneous melanoma. They may be present in patients with multiple melanocytic nevi (atypical nevus syndrome) or is...

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Published inAnais brasileiros de dermatología Vol. 85; no. 6; p. 863
Main Authors Rezze, Gisele Gargantini, Leon, Alexandre, Duprat, João
Format Journal Article
LanguageEnglish
Published Brazil 01.11.2010
Subjects
Dermoscopy
Diagnosis, Differential
Dysplastic Nevus Syndrome - epidemiology
Dysplastic Nevus Syndrome - pathology
Humans
Melanoma - pathology
Precancerous Conditions - epidemiology
Precancerous Conditions - pathology
Skin Neoplasms - epidemiology
Skin Neoplasms - pathology
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Summary:Atypical nevum (dysplastic) is considered an important factor associated with increased risk of developing cutaneous melanoma. It is believed that atypical nevi are precursor lesions of cutaneous melanoma. They may be present in patients with multiple melanocytic nevi (atypical nevus syndrome) or isolated and in small numbers in a non-familial context. The disease usually begins at puberty and predominates in young people. It has a predilection for sun-exposed areas, especially the trunk. The major challenge in relation to atypical nevi lies in the controversy of defining its nomenclature, clinical diagnosis, dermoscopic criteria, histopathological diagnosis and molecular aspects. This review aims at bringing knowledge, facilitating comprehension and clarifying doubts about atypical nevus.
ISSN:1806-4841
DOI:10.1590/S0365-05962010000600013