Enantioselective Copper‐Catalyzed Formal [2+1] and [4+1] Annulations of Diynes with Ketones via Carbonyl Ylides

• Published in: Angewandte Chemie Vol. 134; no. 43
• Main Authors: Qi, Lin‐Jun, Li, Cui‐Ting, Huang, Zheng‐Qi, Jiang, Jia‐Tian, Zhu, Xin‐Qi, Lu, Xin, Ye, Long‐Wu
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 24.10.2022
• Subjects: Alkynes; Annulation; Asymmetric Catalysis; Asymmetry; Carbenes; Carbonyl compounds; Carbonyl Ylides; Carbonyls; Catalysts; Cations; Chemistry; Copper; Divergence; Enantiomers; Epoxidation; Heterocycles; Ketones

Carbonyl ylides have proven to be powerful synthons for the efficient construction of various valuable O‐heterocycles, and the formation of carbonyl ylides by the reaction of metal carbenes with carbonyls has attracted increasing attention over the past decades. However, a catalyst‐controlled highly...