Controllable Si−C Bond Activation Enables Stereocontrol in the Palladium‐Catalyzed [4+2] Annulation of Cyclopropenes with Benzosilacyclobutanes

• Published in: Angewandte Chemie Vol. 132; no. 2; pp. 800 - 807
• Main Authors: Wang, Xing‐Ben, Zheng, Zhan‐Jiang, Xie, Jia‐Le, Gu, Xing‐Wei, Mu, Qiu‐Chao, Yin, Guan‐Wu, Ye, Fei, Xu, Zheng, Xu, Li‐Wen
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 07.01.2020
• Subjects: Activation; Chemical reactions; Chemistry; Enantiomers; Gespannte Moleküle; Heptanes; Organic chemistry; Organic compounds; Palladium; Ringaufweitung; Si-C-Bindungsaktivierung; Silacyclen; Stereoselectivity

A novel and unusual palladium‐catalyzed [4+2] annulation of cyclopropenes with benzosilacyclobutanes is reported. This reaction occurred through chemoselective Si−C(sp2) bond activation in synergy with ring expansion/insertion of cyclopropenes to form new C(sp2)−C(sp3) and Si−C(sp3) bonds. An array...