p38α kinase governs muscle strength through PGC1α in mice

• Published in: Acta Physiologica Vol. 240; no. 11; pp. e14234 - n/a
• Main Authors: Herrera‐Melle, Leticia, Cicuéndez, Beatriz, López, Juan Antonio, Dumesic, Phillip A., Wilensky, Sarah E., Rodríguez, Elena, Leiva‐Vega, Luis, Caballero, Ainoa, León, Marta, Vázquez, Jesús, Spiegelman, Bruce M., Folgueira, Cintia, Mora, Alfonso, Sabio, Guadalupe
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.11.2024
• Subjects: Energy expenditure; Energy metabolism; Homeostasis; Locomotion; Metabolism; Mitochondria; mitochondrial biogenesis; mitochondrial dynamics; Muscle strength; Myoblasts; p38α; Proteomics; Quality of life; Skeletal muscle; muscle strength; skeletal muscle; mitochondrial biogenesis; mitochondrial dynamics; p38α

Aims Skeletal muscle, with its remarkable plasticity and dynamic adaptation, serves as a cornerstone of locomotion and metabolic homeostasis in the human body. Muscle tissue, with its extraordinary capacity for force generation and energy expenditure, plays a fundamental role in the movement, metabo...