Immune modulation and the oral live biotherapeutic product, MRx0518, in treatment-naïve patients with cancer: Updated safety data

• Published in: Journal of clinical oncology Vol. 41; no. 16_suppl; p. 3145
• Main Authors: Dama, Paola, Frampton, Adam Enver, Pickford, Emily, Tookman, Laura, Cunnea, Paula, Fotopoulou, Christina, Liu, Daniel, Clark, James, Lozano-kuehne, Jingky, Badman, Philip David, Clarke, Aaron, Chetal, Sasha, Fyvie, Gayle, Stevenson, Alex, Krell, Jonathan
• Format: Journal Article
• Language: English
• Published: American Society of Clinical Oncology 01.06.2023

3145Background: Live biotherapeutic products (LBPs) are emerging novel anti-cancer therapies. MRx0518 is a gut microbiome-derived oral LBP, consisting of a single strain of Enterococcus gallinarum, which has demonstrated potent anti-tumorigenic efficacy pre-clinically. We have previously shown MRx05...