Rivaroxaban Has Predictable Pharmacokinetics (PK) and Pharmacodynamics (PD) When Given Once or Twice Daily for the Treatment of Acute, Proximal Deep Vein Thrombosis (DVT)

Introduction: Rivaroxaban is an oral, direct Factor Xa inhibitor in clinical development for the prevention and treatment of thromboembolic disorders. Two large, phase IIb, dose-finding studies investigating rivaroxaban for the treatment of acute, proximal DVT, showed that rivaroxaban once daily (od...

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Bibliographic Details
Published inBlood Vol. 110; no. 11; p. 1880
Main Authors Mueck, Wolfgang, Agnelli, Giancarlo, Buller, Harry
Format Journal Article
LanguageEnglish
Published Elsevier Inc 16.11.2007
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