Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA repair gene, O 6 ‐alkylguanine–DNA alkyltransferase

• Published in: International journal of cancer Vol. 122; no. 4; pp. 791 - 795
• Main Authors: Crosbie, Philip A.J., McGown, Gail, Thorncroft, Mary R., O'Donnell, Paul N.S., Barber, Philip V., Lewis, Sarah J., Harrison, Kathryn L., Agius, Raymond M., Santibáñez‐Koref, Mauro F., Margison, Geoffrey P., Povey, Andrew C.
• Format: Journal Article
• Language: English
• Published: 15.02.2008

The association between lung cancer risk and 2 polymorphisms, rs12268840 and rs2308327 (codon K178R), in the DNA repair protein, O 6 ‐alkylguanine–DNA alkyltransferase, which are associated with interindividual differences in activity, have been investigated in 3 hospital‐based case–control studies....