Molecular Uncoupling of Fractalkine-mediated Cell Adhesion and Signal Transduction

Fractalkine is a novel multidomain protein expressed on the surface of activated endothelial cells. Cells expressing the chemokine receptor CX 3 CR1 adhere to fractalkine with high affinity, but it is not known if adherence requires G-protein activation and signal transduction. To investigate the ce...

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Bibliographic Details
Published inThe Journal of biological chemistry Vol. 274; no. 15; pp. 10053 - 10058
Main Authors Haskell, Christopher A., Cleary, Michael D., Charo, Israel F.
Format Journal Article
LanguageEnglish
Published American Society for Biochemistry and Molecular Biology 09.04.1999
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