Macrophage-Derived Foam Cells Separated from Rabbit Atherosclerotic Lesions Observation by a Transmission Electron Microscope and Measurement of Superoxide Production

• Published in: Dōmyaku kōka = The Journal of Japan Atherosclerosis Society Vol. 16; no. 3; pp. 385 - 386
• Main Authors: KUZUYA, Masafumi, KUZUYA, Fumio, HAYASHI, Toshio, FUNAKI, Chiaki, NAITO, Michitaka, ASAI, Kanichi
• Format: Journal Article
• Language: English; Japanese
• Published: Japan Atherosclerosis Society 1988
• Subjects: atherosclerosis; foam cell; macrophage; microvilli; superoxide

We observed macrophage-derived foam cells separated from rabbit atherosclerotic lesions by a transmission electron microscope. Most of them are heavily lipid-laden, with a peripheral nucleus and have many microvilli in contrast to rabbit blood monocytes, which rarely have microvilli. Macrophage-deri...