Cover Feature: Cellular Mechanistic Considerations on Cytotoxic Mode of Action of Phosphino Ru(II) and Ir(III) Complexes (Eur. J. Inorg. Chem. 33/2023)

• Published in: European journal of inorganic chemistry Vol. 26; no. 33
• Main Authors: Wojtala, Daria B., Komarnicka, Urszula K., Kyzioł, Agnieszka, Kozieł, Sandra, Szmitka, Magdalena, Słowikowski, Mateusz, Kulczyńska, Julia, Stochel, Grażyna
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 24.11.2023
• Subjects: Cancer; Cellular mechanism of action; Chemotherapeutics; Chloride ions; Gloves; Inorganic chemistry; Iridium(III); Organometallic compounds; Phosphines; Ruthenium compounds; Ruthenium(II)
• DOI: 10.1002/ejic.202300637
• ISSN: 1434-1948

The Cover Feature shows the fight of a phosphino Ru (or Ir) organometallic compound (left) with a cancer cell (right) in the boxing ring. The cancer cell, which is depicted as an ugly, green monster with three eyes, is wearing a yellow‐orange t‐shirt and red boxing gloves. The X‐ray structure of the Ru organometallic compound is presented with orange phosphorus, dark green ruthenium, and light green chloride ions. The ruthenium complex is not even wearing boxing gloves, because it is very sure that it can easily beat the cancer cell and win the fight. More information can be found in the Research Article by U. K. Komarnicka, A. Kyzioł and co‐workers.