Auranofin and D-penicillamine: a one year comparative study of safety and efficacy in patients with rheumatoid arthritis followed by a two year open assessment of auranofin

• Published in: Clinical rheumatology Vol. 3 Suppl 1; p. 75
• Main Authors: Franchimont, P, Hauwaert, C, Vanschoubroek, K
• Format: Journal Article
• Language: English
• Published: Germany 01.03.1984
• Subjects: Adult; Aged; Anti-Inflammatory Agents - therapeutic use; Arthritis, Rheumatoid - blood; Arthritis, Rheumatoid - drug therapy; Arthritis, Rheumatoid - immunology; Auranofin; Aurothioglucose - analogs & derivatives; Aurothioglucose - therapeutic use; Female; Follow-Up Studies; Gold - analogs & derivatives; Gold - blood; Humans; Immunoglobulins - analysis; Male; Middle Aged; Penicillamine - therapeutic use

Forty-six patients with classical or definite rheumatoid arthritis participated in a prospective clinical trial comparing auranofin 6 mg/day (26 patients) with D-penicillamine 500 mg/day (20 patients) during one year. NSAIDs were also given throughout the study period. After the first year, patients...