VAX014 for instillation in subjects with nonmuscle-invasive bladder cancer

• Published in: Journal of clinical oncology Vol. 40; no. 6_suppl; p. 488
• Main Authors: Lerner, Seth P., Karsh, Lawrence Ivan, O'Donnell, Michael A., Shore, Neal D., Lotan, Yair, Tsuji, Shingo, Giacalone, Matthew
• Format: Journal Article
• Language: English
• Published: American Society of Clinical Oncology 20.02.2022

488 Background: VAX014 is a novel tumor targeted oncolytic agent for intravesical administration. It is comprised of recombinant bacterial minicells, that actively target a3b1 and a5b1 integrins expressed on NMIBC and deliver an active cytotoxic/oncolytic protein payload, perfringolysin O. VAX014 is...