Bronze baby syndrome
A newborn female infant suddenly developed a generalized gray-brown discoloration of her skin while receiving phototherapy for hyperbilirubinemia. The discoloration waned over the succeeding weeks. Her serum contained an unknown pigment that had a characteristic absorbance on spectrophotometry. The...
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| Published in | Journal of the American Academy of Dermatology Vol. 12; no. 2; pp. 325 - 328 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Mosby, Inc
01.02.1985
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| Online Access | Get full text |
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| Abstract | A newborn female infant suddenly developed a generalized gray-brown discoloration of her skin while receiving phototherapy for hyperbilirubinemia. The discoloration waned over the succeeding weeks. Her serum contained an unknown pigment that had a characteristic absorbance on spectrophotometry. The distinctive findings and some possible causes of the bronze baby syndrome are discussed. The findings are compared to other causes of dusky-hued skin in the neonate. The bronze baby syndrome is usually innocuous but can signal life-threatening disease. |
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| AbstractList | A newborn female infant suddenly developed a generalized gray-brown discoloration of her skin while receiving phototherapy for hyperbilirubinemia. The discoloration waned over the succeeding weeks. Her serum contained an unknown pigment that had a characteristic absorbance on spectrophotometry. The distinctive findings and some possible causes of the bronze baby syndrome are discussed. The findings are compared to other causes of dusky-hued skin in the neonate. The bronze baby syndrome is usually innocuous but can signal life-threatening disease. |
| Author | Burgdorf, Walter H.C. Ashley, John R. Brann, Ben S. Littler, Curt M. |
| Author_xml | – sequence: 1 givenname: John R. surname: Ashley fullname: Ashley, John R. organization: From the Departments of Dermatology University of Oklahoma College of Medicine – sequence: 2 givenname: Curt M. surname: Littler fullname: Littler, Curt M. organization: From the Departments of Dermatology University of Oklahoma College of Medicine – sequence: 3 givenname: Walter H.C. surname: Burgdorf fullname: Burgdorf, Walter H.C. organization: From the Departments of Dermatology University of Oklahoma College of Medicine – sequence: 4 givenname: Ben S. surname: Brann fullname: Brann, Ben S. organization: Pediatrics University of Oklahoma College of Medicine |
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| CitedBy_id | crossref_primary_10_3345_kjp_2019_00528 crossref_primary_10_1016_S0190_9622_87_80056_7 crossref_primary_10_1080_08035250410025159 crossref_primary_10_1016_S0190_9622_88_70036_5 crossref_primary_10_1111_j_1651_2227_2005_tb02020_x |
| Cites_doi | 10.1111/j.1651-2227.1982.tb09444.x 10.1203/00006450-198305000-00004 10.1542/peds.69.3.273 10.1111/j.1651-2227.1982.tb09443.x 10.1016/S0344-0338(81)80135-5 10.1177/000992288202100910 10.1016/S0022-3476(72)80172-0 10.1001/archderm.1978.01640170075017 10.1016/S0022-3476(76)80268-5 10.1056/NEJM195912242612604 |
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| Copyright | 1985 American Academy of Dermatology, Inc. |
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| References | Ruis-Malmonade, Tamaya, Fernandez-Diez (bib6) 1978; 114 Burns, Hodgman, Carr (bib8) 1959; 261 Krasinski, Perkin, Rutledge (bib9) 1982; 21 Onishi, Itah, Isabe (bib4) 1982; 69 Kopelman, Brown, Odell (bib1) 1972; 81 Sutherland (bib7) 1959; 97 Clark, Shaze, Hamamoto (bib10) 1976; 88 Tan, Jacob (bib2) 1982; 71 Balazs, Mark, Lukacs (bib3) 1981; 172 Ebbesen (bib11) 1982; 71 Rubaltelli, Jori, Reddie (bib5) 1983; 17 Sutherland (10.1016/S0190-9622(85)80045-1_bib7) 1959; 97 Kopelman (10.1016/S0190-9622(85)80045-1_bib1) 1972; 81 Ebbesen (10.1016/S0190-9622(85)80045-1_bib11) 1982; 71 Tan (10.1016/S0190-9622(85)80045-1_bib2) 1982; 71 Onishi (10.1016/S0190-9622(85)80045-1_bib4) 1982; 69 Krasinski (10.1016/S0190-9622(85)80045-1_bib9) 1982; 21 Ruis-Malmonade (10.1016/S0190-9622(85)80045-1_bib6) 1978; 114 Rubaltelli (10.1016/S0190-9622(85)80045-1_bib5) 1983; 17 Burns (10.1016/S0190-9622(85)80045-1_bib8) 1959; 261 Balazs (10.1016/S0190-9622(85)80045-1_bib3) 1981; 172 Clark (10.1016/S0190-9622(85)80045-1_bib10) 1976; 88 |
| References_xml | – volume: 261 start-page: 1318 year: 1959 end-page: 1321 ident: bib8 article-title: Fatal circulatory collapse in premature infants receiving chloramphenicol publication-title: N Engl J Med contributor: fullname: Carr – volume: 81 start-page: 466 year: 1972 end-page: 472 ident: bib1 article-title: The bronze baby syndrome: A complication of phototherapy publication-title: J Pediatr contributor: fullname: Odell – volume: 21 start-page: 571 year: 1982 end-page: 572 ident: bib9 article-title: Grey baby syndrome revisited publication-title: Clin Pediatr (Phila) contributor: fullname: Rutledge – volume: 88 start-page: 461 year: 1976 end-page: 464 ident: bib10 article-title: The bronze baby syndrome: Postmortem data publication-title: J Pediatr contributor: fullname: Hamamoto – volume: 172 start-page: 196 year: 1981 end-page: 204 ident: bib3 article-title: Light and electron microscopic studies of the liver in bronze baby syndrome publication-title: Pathol Res Pract contributor: fullname: Lukacs – volume: 71 start-page: 415 year: 1982 end-page: 420 ident: bib11 article-title: Low reserve albumin for binding of bilirubin in neonates with deficiency of bilirubin excretion and bronze baby syndrome publication-title: Acta Paediatr Scand contributor: fullname: Ebbesen – volume: 71 start-page: 409 year: 1982 end-page: 414 ident: bib2 article-title: The bronze baby syndrome publication-title: Acta Paediatr Scand contributor: fullname: Jacob – volume: 17 start-page: 327 year: 1983 end-page: 330 ident: bib5 article-title: Bronze baby syndrome: A new porphyrin-related disorder publication-title: Pediatr Res contributor: fullname: Reddie – volume: 69 start-page: 273 year: 1982 end-page: 276 ident: bib4 article-title: Mechanism of development of bronze baby syndrome in neonates treated with phototherapy publication-title: Pediatrics contributor: fullname: Isabe – volume: 114 start-page: 775 year: 1978 end-page: 778 ident: bib6 article-title: Universal acquired melanosis: The carbon baby publication-title: Arch Dermatol contributor: fullname: Fernandez-Diez – volume: 97 start-page: 761 year: 1959 end-page: 767 ident: bib7 article-title: Fatal cardiovascular collapse of infants receiving large amounts of chloramphenicol publication-title: AMA J Dis Child contributor: fullname: Sutherland – volume: 71 start-page: 415 year: 1982 ident: 10.1016/S0190-9622(85)80045-1_bib11 article-title: Low reserve albumin for binding of bilirubin in neonates with deficiency of bilirubin excretion and bronze baby syndrome publication-title: Acta Paediatr Scand doi: 10.1111/j.1651-2227.1982.tb09444.x contributor: fullname: Ebbesen – volume: 17 start-page: 327 year: 1983 ident: 10.1016/S0190-9622(85)80045-1_bib5 article-title: Bronze baby syndrome: A new porphyrin-related disorder publication-title: Pediatr Res doi: 10.1203/00006450-198305000-00004 contributor: fullname: Rubaltelli – volume: 69 start-page: 273 year: 1982 ident: 10.1016/S0190-9622(85)80045-1_bib4 article-title: Mechanism of development of bronze baby syndrome in neonates treated with phototherapy publication-title: Pediatrics doi: 10.1542/peds.69.3.273 contributor: fullname: Onishi – volume: 71 start-page: 409 year: 1982 ident: 10.1016/S0190-9622(85)80045-1_bib2 article-title: The bronze baby syndrome publication-title: Acta Paediatr Scand doi: 10.1111/j.1651-2227.1982.tb09443.x contributor: fullname: Tan – volume: 172 start-page: 196 year: 1981 ident: 10.1016/S0190-9622(85)80045-1_bib3 article-title: Light and electron microscopic studies of the liver in bronze baby syndrome publication-title: Pathol Res Pract doi: 10.1016/S0344-0338(81)80135-5 contributor: fullname: Balazs – volume: 21 start-page: 571 year: 1982 ident: 10.1016/S0190-9622(85)80045-1_bib9 article-title: Grey baby syndrome revisited publication-title: Clin Pediatr (Phila) doi: 10.1177/000992288202100910 contributor: fullname: Krasinski – volume: 97 start-page: 761 year: 1959 ident: 10.1016/S0190-9622(85)80045-1_bib7 article-title: Fatal cardiovascular collapse of infants receiving large amounts of chloramphenicol publication-title: AMA J Dis Child contributor: fullname: Sutherland – volume: 81 start-page: 466 year: 1972 ident: 10.1016/S0190-9622(85)80045-1_bib1 article-title: The bronze baby syndrome: A complication of phototherapy publication-title: J Pediatr doi: 10.1016/S0022-3476(72)80172-0 contributor: fullname: Kopelman – volume: 114 start-page: 775 year: 1978 ident: 10.1016/S0190-9622(85)80045-1_bib6 article-title: Universal acquired melanosis: The carbon baby publication-title: Arch Dermatol doi: 10.1001/archderm.1978.01640170075017 contributor: fullname: Ruis-Malmonade – volume: 88 start-page: 461 year: 1976 ident: 10.1016/S0190-9622(85)80045-1_bib10 article-title: The bronze baby syndrome: Postmortem data publication-title: J Pediatr doi: 10.1016/S0022-3476(76)80268-5 contributor: fullname: Clark – volume: 261 start-page: 1318 year: 1959 ident: 10.1016/S0190-9622(85)80045-1_bib8 article-title: Fatal circulatory collapse in premature infants receiving chloramphenicol publication-title: N Engl J Med doi: 10.1056/NEJM195912242612604 contributor: fullname: Burns |
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