Tamibarotene Compared to All-Trans Retinoic Acid (ATRA) As Add-on to Arsenic Trioxide (ATO) in Subjects with Relapsed Acute Promyelocytic Leukemia (APL)

• Published in: Blood Vol. 126; no. 23; p. 220
• Main Authors: Wang, Jianxiang, Mi, Yingchang, Jiang, Bin, Chen, Xiequn, Ji, Chunyan, Li, Yan, Zhao, Xielan, Lai, Yongrong, Hu, Yu, Tang, Aiping, Liu, Ting, Jin, Jie, Li, Junmin, Yang, Linhua, Li, Jianyong, Meng, Fanyi
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 03.12.2015

Background Combination therapy with ATRA and ATO is a standard therapy for relapsed APL. Despite the high complete remission (CR) rate with ATRA-ATO combination therapy, patients administered this combination for relapsed disease may acquire tolerance to ATRA, which reduces the CR rate in relapsed A...