Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort

• Published in: Frontiers in pharmacology Vol. 15
• Main Authors: Reyes-Reyes, Elizabeth, Herrera-Isidrón, José Alfredo, Cuétara-Lugo, Elizabeth, Shkedy, Zhiv, Valkenborg, Dirk, Pérez-Novo, Claudina Angela, Fernández-Peña, Gisselle, González-Pérez, Idania, Fernández-Pérez, Miguel David, Vanden-Berghe, Wim, Rodeiro-Guerra, Idania
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 27.09.2024
• Subjects: admixed population; Cuban population; genetic variants; pharmacogenetic; precision medicine; single-nucleotide variants

Introduction The Cuban population is genetically diverse, and information on the prevalence of genetic variants is still limited. As complex admixture processes have occurred, we hypothesized that the frequency of pharmacogenetic variants and drug responses may vary within the country. The aims of t...